Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.52 |
| ▸ | TERT | O14746 | 4/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23011442 | 0.89 | LTA4H (0.50) | LTA4HTERTTRPV1SPHK1ADRB2 | |
| SCHEMBL12634418 | 0.88 | SPHK1 (0.51) | LTA4HSPHK1SPHK2 | |
| SCHEMBL17801791 | 0.88 | SPHK1 (0.51) | LTA4HSPHK1SPHK2 | |
| SCHEMBL15602566 | 0.84 | HDAC3 (0.51) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL29142412 | 0.78 | TRPV1 (0.43) | LTA4HTRPV1HDAC3HDAC4HDAC1 | |
| SCHEMBL18867987 | 0.78 | SPHK1 (0.49) | LTA4HSPHK1SPHK2 | |
| SCHEMBL31063980 | 0.78 | SPHK1 (0.40) | SPHK1HDAC1HDAC6SPHK2 | |
| SCHEMBL19132239 | 0.78 | HDAC2 (0.41) | SPHK1HDAC1HDAC2HDAC6SPHK2 | |
| SCHEMBL19234501 | 0.77 | SPHK1 (0.53) | LTA4HSPHK1HDAC3HDAC4HDAC1 | |
| SCHEMBL18099876 | 0.77 | HSD17B10 (0.49) | TRPV1SPHK1SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3169368-B1 | LINKERS AND THEIR APPLICATION TOWARDS ADC | MEDSHINE DISCOVERY INC (CN) | 2021-02-17 | — | — | EP | disclosed |
| US-10280229-B2 | Linkers and their application towards ADC | MEDSHINE DISCOVERY INC. (CN) | 2019-05-07 | — | — | US | disclosed |
| US-20170202974-A1 | LINKERS AND THEIR APPLICATION TOWARDS ADC | MEDSHINE DISCOVERY INC. (CN) | 2017-07-20 | — | — | US | disclosed |
| WO-2016008392-A1 | LINKERS AND THEIR APPLICATION TOWARDS ADC | MEDSHINE DISCOVERY INC. (CN) | 2016-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170202974-A1 | LINKERS AND THEIR APPLICATION TOWARDS ADC | DNPEP, DPP7, DPP3 | LTA4H 1205/4885TERT 3413/4885TRPV1 3920/4885 |
| US-10280229-B2 | Linkers and their application towards ADC | DNPEP, DPP7, DPP3 | LTA4H 1205/4885TERT 3413/4885TRPV1 3920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.