Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 6/20 | 0.37 |
| ▸ | ANPEP | P15144 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.31 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13738649 | 1.00 | MMP2 (0.37) | MMP2ANPEPCYP1A2HIF1AKMT2A | |
| SCHEMBL15873018 | 0.82 | ACE (0.33) | ATMCAPN1 | |
| SCHEMBL15875604 | 0.82 | ACE (0.33) | ATMCAPN1 | |
| SCHEMBL25184479 | 0.82 | ACE (0.33) | ATMCAPN1 | |
| SCHEMBL15875605 | 0.82 | ACE (0.33) | ATMCAPN1 | |
| SCHEMBL13866573 | 0.80 | PTPN1 (0.37) | MMP2ANPEPBRD4ALDH1A1 | |
| SCHEMBL2601624 | 0.80 | PTPN1 (0.37) | MMP2ANPEPBRD4ALDH1A1 | |
| SCHEMBL2605610 | 0.80 | PTPN1 (0.37) | MMP2ANPEPBRD4ALDH1A1 | |
| SCHEMBL12105257 | 0.80 | PTPN1 (0.37) | MMP2ANPEPBRD4ALDH1A1 | |
| SCHEMBL882834 | 0.80 | PTPN1 (0.37) | MMP2ANPEPBRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016010897-A1 | BICYCLIC HETEROAROMATIC CARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS | INCYTE CORPORATION (US) | 2016-01-21 | — | — | WO | disclosed |