Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DTYMK | P23919 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.42 |
| ▸ | GSTM2 | P28161 | 2/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29353295 | 0.86 | DTYMK (1.00) | DTYMKTSHRMEN1KMT2AMAPT | |
| SCHEMBL26775 | 0.86 | DTYMK (1.00) | DTYMKTSHRMEN1KMT2AMAPT | |
| SCHEMBL143541 | 0.86 | DTYMK (1.00) | DTYMKTSHRMEN1KMT2AMAPT | |
| SCHEMBL29388000 | 0.84 | DTYMK (0.97) | DTYMKTSHRMEN1KMT2AMAPT | |
| SCHEMBL8577281 | 0.84 | DTYMK (0.97) | DTYMKTSHRMEN1KMT2AMAPT | |
| SCHEMBL30534229 | 0.84 | POLB (0.57) | DTYMKTSHRMEN1KMT2AMAPT | |
| SCHEMBL4904 | 0.84 | POLB (0.57) | DTYMKTSHRMEN1KMT2AMAPT | |
| SCHEMBL1043222 | 0.84 | POLB (0.57) | DTYMKTSHRMEN1KMT2AMAPT | |
| SCHEMBL12269946 | 0.79 | DTYMK (0.85) | DTYMKMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL19885315 | 0.79 | DTYMK (0.85) | DTYMKTSHRMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2386551-A1 | Novel compounds, pharmaceutical compositions containing same, and methods of use for same | Fasgen Inc. (US) | 2011-11-16 | — | — | EP | disclosed |
| US-8038089-B2 | Leader member in recording tape cartridge, manufacturing method thereof, and recording tape cartridge | FUJIFILM CORPORATION (JP) | 2011-10-18 | — | — | US | disclosed |