⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1777383 | 0.76 | — | — | |
| SCHEMBL2444396 | 0.76 | — | — | |
| SCHEMBL1904553 | 0.76 | — | — | |
| SCHEMBL19438929 | 0.74 | DAO (0.36) | — | |
| SCHEMBL10908855 | 0.73 | — | — | |
| SCHEMBL16324771 | 0.73 | — | — | |
| SCHEMBL1306770 | 0.73 | — | — | |
| SCHEMBL29991984 | 0.71 | DAO (0.34) | — | |
| SCHEMBL5713341 | 0.71 | DAO (0.50) | — | |
| SCHEMBL1651954 | 0.71 | FDPS (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12319698-B2 | Proteasome activity enhancing compounds | Kineta, Inc. (US) | 2025-06-03 | — | — | US | disclosed |
| CN-112585132-B | Proteasome activity enhancing compounds | 优曼尼蒂公司 | 2025-02-28 | — | — | CN | disclosed |
| WO-2023118521-A1 | DIHYDRO-OXAZOL DERIVATIVE COMPOUNDS | AC IMMUNE SA (CH) | 2023-06-29 | — | — | WO | disclosed |
| US-20230183256-A1 | PROTEASOME ACTIVITY ENHANCING COMPOUNDS | YUMANITY THERAPEUTICS, INC. | 2023-06-15 | — | — | US | disclosed |
| US-11560385-B2 | Proteasome activity enhancing compounds | PROTEOSTASIS THERAPEUTICS, INC. (US) | 2023-01-24 | — | — | US | disclosed |
| US-11358957-B2 | Microbiocidal oxadiazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2022-06-14 | — | — | US | disclosed |
| CN-112778377-B | Ferrocene burning-rate catalyst containing bis (imidazole or pyrazole-1, 2, 3-triazole) group and preparation method thereof | 陕西师范大学 | 2021-12-24 | — | — | CN | disclosed |
| CN-112939708-B | Imidazole and pyrazole combustion rate catalyst containing ferrocenyl methyl-1, 2, 3-triazolyl group and preparation method thereof | 陕西师范大学 | 2021-11-30 | — | — | CN | disclosed |
| US-20210188758-A1 | PHENOXY ACETIC ACIDS AND PHENYL PROPIONIC ACIDS AS PPAR DELTA AGONISTS | VTVX HOLDINGS II LLC | 2021-06-24 | — | — | US | disclosed |
| CN-112939708-A | Imidazole and pyrazole combustion rate catalyst containing ferrocenyl methyl-1, 2, 3-triazolyl group and preparation method thereof | 陕西师范大学 | 2021-06-11 | — | — | CN | disclosed |
| EP-1038880-B1 | Androstanes and pregnanes for allosteric modulation of GABA receptor | EURO CELTIQUE SA (LU) | 2007-10-17 | — | — | EP | disclosed |
| WO-2007071766-A2 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | TRANSTECH PHARMA (US) | 2007-06-28 | — | — | WO | disclosed |
| US-6277838-B1 | ADMINISTERING DOSAGE OF ANXIOLYTIC AGENT TO ANIMAL | COCENSYS, INC. | 2001-08-21 | — | — | US | disclosed |
| US-6143736-A | USED TO ALLEVIATE STRESS, ANXIETY, SEIZURES, MOOD DISORDERS, PREMENSTRUAL SYNDROME(PMS) AND POSTNATAL DEPRESSION (PND AND TO INDUCE ANESTHESIA | COCENSYS, INC. (US) | 2000-11-07 | — | — | US | disclosed |
| EP-1038880-A2 | Androstanes and pregnanes for allosteric modulation of GABA receptor | COCENSYS, INC. (US) | 2000-09-27 | — | — | EP | disclosed |
| EP-0752860-B1 | ANDROSTANES AND PREGNANES FOR ALLOSTERIC MODULATION OF GABA RECEPTOR | EURO CELTIQUE SA (LU) | 2000-08-23 | — | — | EP | disclosed |
| US-5939545-A | MODULATING THE GABA.SUB.A (GAMMA-AMINOBUTYRIC ACID A) RECEPTOR-CHLORIDE IONOPHORE COMPLEX TO ALLEVIATE STRESS, ANXIETY, SEIZURES, MOOD DISORDERS, PMS (PREMENSTRUAL SYNDROME) AND PND (POSTNATAL DEPRESSION) AND TO INDUCE ANESTHESIA | COCENSYS, INC. (US) | 1999-08-17 | — | — | US | disclosed |
| EP-0752860-A4 | ANDROSTANES AND PREGNANES FOR ALLOSTERIC MODULATION OF GABA RECEPTOR | COCENSYS INC (US) | 1998-05-06 | — | — | EP | disclosed |
| EP-0752860-A1 | ANDROSTANES AND PREGNANES FOR ALLOSTERIC MODULATION OF GABA RECEPTOR | COCENSYS, INC. (US) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995021617-A1 | ANDROSTANES AND PREGNANES FOR ALLOSTERIC MODULATION OF GABA RECEPTOR | COCENSYS, INC. (US) | 1995-08-17 | — | — | WO | disclosed |