SCHEMBL17449486

SCHEMBL17449486

C=CC(=O)OCCCCOCC(COC(=O)C(=C)C)OCP(=O)(OCC)OCC

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.40
HPGD P15428 1/20 0.40
ALDH1A1 P00352 3/20 0.37
CYP3A4 P08684 1/20 0.37
LPAR1 Q92633 4/20 0.36
LPAR3 Q9UBY5 4/20 0.36
THRB P10828 2/20 0.34
LPAR2 Q9HBW0 1/20 0.32
TP53 P04637 2/20 0.31
HIF1A Q16665 2/20 0.31
HSD17B10 Q99714 1/20 0.31
AKT1 P31749 2/20 0.31
AKT2 P31751 2/20 0.31
AKT3 Q9Y243 2/20 0.31
PIK3R1 P27986 1/20 0.31
PIK3CA P42336 1/20 0.31
PLA2G2C Q5R387 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17448871 0.89 TSHR (0.40) TSHRHPGDALDH1A1CYP3A4LPAR1
SCHEMBL17449488 0.89 TSHR (0.39) TSHRHPGDALDH1A1THRB
SCHEMBL17449489 0.83 TSHR (0.46) TSHRALDH1A1THRB
SCHEMBL17448870 0.77 TSHR (0.42) TSHRHPGDALDH1A1CYP3A4THRB
SCHEMBL17448866 0.75 TSHR (0.49) TSHRHPGDALDH1A1CYP3A4THRB
SCHEMBL20357782 0.72 TSHR (0.58) TSHRHPGDALDH1A1CYP3A4THRB
SCHEMBL8740819 0.71 TSHR (0.51) TSHRALDH1A1LPAR1LPAR3THRB
SCHEMBL9681045 0.71 TSHR (0.65) TSHRHPGDALDH1A1CYP3A4THRB
SCHEMBL11522990 0.71 TSHR (0.60) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL278845 0.71 TSHR (0.42) TSHRLPAR1LPAR3THRBLPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10233350-B2 Photocurable composition and enveloped device including same CHEIL INDUSTRIES, INC. (KR) 2019-03-19 US disclosed
US-20160017170-A1 PHOTOCURABLE COMPOSITION AND ENVELOPED DEVICE INCLUDING SAME CHEIL INDUSTRIES INC. (KR) 2016-01-21 US disclosed