Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.47 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 3/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30913266 | 0.82 | PTGDR2 (0.48) | PTGDR2KIF11PTGDRMETAP2METAP1 | |
| SCHEMBL198311 | 0.82 | PTGDR2 (0.48) | PTGDR2KIF11PTGDRMETAP2METAP1 | |
| SCHEMBL198081 | 0.82 | PTGDR2 (0.48) | PTGDR2KIF11PTGDRMETAP2METAP1 | |
| SCHEMBL1825802 | 0.82 | PTGDR2 (0.48) | PTGDR2KIF11PTGDRMETAP2METAP1 | |
| Hydrochloric Acid SCHEMBL8869405 | 0.81 | PTGDR2 (0.47) | PTGDR2KIF11PTGDRKMOPTGS2 | |
| SCHEMBL28565924 | 0.81 | PTGDR2 (0.47) | PTGDR2PTGDRKMOPTGS2 | |
| SCHEMBL2062948 | 0.80 | PTGDR2 (0.45) | PTGDR2KIF11PTGDRKMOPTGS2 | |
| SCHEMBL418663 | 0.80 | PTGDR2 (0.45) | PTGDR2KIF11PTGDRKMOPTGS2 | |
| SCHEMBL415803 | 0.80 | PTGDR2 (0.45) | PTGDR2KIF11PTGDRKMOPTGS2 | |
| SCHEMBL6688085 | 0.79 | PTGDR2 (0.42) | PTGDR2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385951-A2 | PHOSPHORAMIDATE DERIVATIVES OF GUANOSINE NUCLEOSIDE COMPOUNDS FOR TREATMENT OF VIRAL INFECTIONS | University College Cardiff Consultants, Ltd. (GB) | 2011-11-16 | — | — | EP | disclosed |
| US-20110254856-A1 | MOBILE TERMINAL AND METHOD OF CONTROLLING OPERATION OF THE MOBILE TERMINAL | LG ELECTRONICS INC. (KR) | 2011-10-20 | — | — | US | disclosed |
| WO-2010081082-A2 | PHOSPHORAMIDATE DERIVATIVES OF GUANOSINE NUCLEOSIDE COMPOUNDS FOR TREATMENT OF VIRAL INFECTIONS | UNIVERSITY COLLEGE OF CARDIFF CONSULTANTS LIMITED (GB) | 2010-07-15 | — | — | WO | disclosed |