SCHEMBL415803

SCHEMBL415803

O=C(O)C(O)c1ccccc1C1CCCC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 3/20 0.45
LMNA P02545 3/20 0.42
MAPK1 P28482 1/20 0.42
PTGDR Q13258 1/20 0.37
KMO O15229 1/20 0.36
USP2 O75604 1/20 0.35
CYP1A2 P05177 1/20 0.35
HTR1A P08908 1/20 0.35
ADRA2A P08913 1/20 0.35
CYP2D6 P10635 1/20 0.35
CHRM1 P11229 1/20 0.35
CYP2C9 P11712 1/20 0.35
DRD1 P21728 1/20 0.35
TBXA2R P21731 1/20 0.35
PTGS1 P23219 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
ADRA1A P35348 1/20 0.35
OPRM1 P35372 1/20 0.35
DRD3 P35462 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL418663 1.00 PTGDR2 (0.45) PTGDR2LMNAMAPK1PTGDRKMO
SCHEMBL2062948 1.00 PTGDR2 (0.45) PTGDR2LMNAMAPK1PTGDRKMO
SCHEMBL198311 0.98 PTGDR2 (0.48) PTGDR2LMNAMAPK1PTGDRKMO
SCHEMBL198081 0.98 PTGDR2 (0.48) PTGDR2LMNAMAPK1PTGDRKMO
SCHEMBL1825802 0.98 PTGDR2 (0.48) PTGDR2LMNAMAPK1PTGDRKMO
SCHEMBL30913266 0.98 PTGDR2 (0.48) PTGDR2LMNAMAPK1PTGDRKMO
Hydrochloric Acid SCHEMBL8869405 0.97 PTGDR2 (0.47) PTGDR2LMNAMAPK1PTGDRKMO
SCHEMBL2062720 0.86 PTGDR2 (0.42) PTGDR2USP2CYP1A2HTR1AADRA2A
SCHEMBL28336946 0.83 PTGDR2 (0.43) PTGDR2LMNAPTGDRKMOUSP2
SCHEMBL7919662 0.83 PTGDR2 (0.43) PTGDR2KMOKDM4EPTGS2PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12358908-B2 Crystals, preparation method and application of a muscarinic receptor antagonist BEIJING SHOWBY PHARMACEUTICAL CO., LTD. (CN) 2025-07-15 US claimed
EP-3842419-B1 METHOD OF MAKING THREO GLYCOPYRROLATE TOSYLATE JOURNEY MEDICAL CORP (US) 2024-04-03 EP claimed
CN-113461585-B Synthesis process of glycopyrronium bromide 安徽普利药业有限公司 2023-10-31 CN claimed
US-20230167107-A1 CRYSTALS, PREPARATION METHOD AND APPLICATION OF A MUSCARINIC RECEPTOR ANTAGONIST BEIJING SHOWBY PHARMACEUTICAL CO., LTD. (CN) 2023-06-01 US claimed
EP-4144733-A1 CRYSTAL OF M RECEPTOR ANTAGONIST AS WELL AS PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Beijing Showby Pharmaceutical Co., Ltd. (CN) 2023-03-08 EP claimed
US-11542232-B2 Process for production of glycopyrronium tosylate JOURNEY MEDICAL CORPORATION (US) 2023-01-03 US claimed
CN-115397823-A M receptor antagonist crystal, preparation method and application thereof 北京硕佰医药科技有限责任公司 2022-11-25 CN claimed
EP-3842419-A1 METHOD OF MAKING THREO GLYCOPYRROLATE TOSYLATE Dermira, Inc. (US) 2021-06-30 EP claimed
US-20210002219-A1 PROCESS FOR PRODUCTION OF GLYCOPYRRONIUM TOSYLATE SWK FUNDING LLC 2021-01-07 US claimed
US-20200330430-A1 GLYCOPYRROLATE SALTS SWK FUNDING LLC 2020-10-22 US claimed
US-20190225580-A1 PROCESS FOR PRODUCTION OF GLYCOPYRRONIUM TOSYLATE DERMIRA, INC. 2019-07-25 US claimed
US-10294201-B2 Process for production of glycopyrronium tosylate DERMIRA, INC. (US) 2019-05-21 US claimed
US-20180186735-A1 PROCESS FOR PRODUCTION OF GLYCOPYRRONIUM TOSYLATE SWK FUNDING LLC 2018-07-05 US claimed
US-9926270-B2 Process for production of glycopyrronium tosylate DERMIRA, INC. (US) 2018-03-27 US claimed
US-20160052879-A1 PROCESS FOR PRODUCTION OF GLYCOPYRRONIUM TOSYLATE SWK FUNDING LLC 2016-02-25 US claimed
EP-2961734-A1 GLYCOPYRROLATE SALTS Dermira, Inc. (US) 2016-01-06 EP claimed
WO-2014134510-A1 GLYCOPYRROLATE SALTS DERMIRA, INC. (US) 2014-09-04 WO claimed
EP-2485678-A1 COFERONS AND METHODS OF MAKING AND USING THEM Cornell University (US) 2012-08-15 EP claimed
WO-2011043817-A1 COFERONS AND METHODS OF MAKING AND USING THEM CORNELL UNIVERSITY (US) 2011-04-14 WO claimed
US-20090005577-A1 Method of producing 1-substituted 3-pyrrolates KRAIOUCHKINE NIKOLAI 2009-01-01 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210002219-A1 PROCESS FOR PRODUCTION OF GLYCOPYRRONIUM TOSYLATE TPO, GYPA, THRA PTGDR2 1783/4885LMNA 4690/4885MAPK1 4111/4885
US-20090005577-A1 Method of producing 1-substituted 3-pyrrolates GYPA, GIPR, PGA5 PTGDR2 863/4885LMNA 4465/4885MAPK1 3486/4885
US-20160052879-A1 PROCESS FOR PRODUCTION OF GLYCOPYRRONIUM TOSYLATE TPO, GYPA, THRA PTGDR2 1783/4885LMNA 4690/4885MAPK1 4111/4885
US-20230167107-A1 CRYSTALS, PREPARATION METHOD AND APPLICATION OF A MUSCARINIC RECEPTOR ANTAGONIST CHRM5, CHRM2, CHRM3 PTGDR2 1017/4885LMNA 3370/4885MAPK1 1551/4885
US-20200330430-A1 GLYCOPYRROLATE SALTS GYPA, GHSR, GALR3 PTGDR2 594/4885LMNA 4757/4885MAPK1 3956/4885
US-20180186735-A1 PROCESS FOR PRODUCTION OF GLYCOPYRRONIUM TOSYLATE TPO, GYPA, THRA PTGDR2 1783/4885LMNA 4690/4885MAPK1 4111/4885
US-10294201-B2 Process for production of glycopyrronium tosylate TPO, GYPA, THRA PTGDR2 1783/4885LMNA 4690/4885MAPK1 4111/4885
US-20190225580-A1 PROCESS FOR PRODUCTION OF GLYCOPYRRONIUM TOSYLATE TPO, GYPA, THRA PTGDR2 1783/4885LMNA 4690/4885MAPK1 4111/4885
US-12358908-B2 Crystals, preparation method and application of a muscarinic receptor antagonist CHRM5, CHRM2, CHRM3 PTGDR2 1017/4885LMNA 3370/4885MAPK1 1551/4885
US-11542232-B2 Process for production of glycopyrronium tosylate TPO, GYPA, THRA PTGDR2 1783/4885LMNA 4690/4885MAPK1 4111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.