Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15072576 | 0.92 | PTGS2 (0.81) | PTGS2 | |
| SCHEMBL15072583 | 0.91 | PTGS2 (0.82) | PTGS2 | |
| SCHEMBL15072462 | 0.91 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL15072579 | 0.90 | PTGS2 (0.80) | PTGS2 | |
| SCHEMBL15072466 | 0.89 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL15072460 | 0.87 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL17453250 | 0.85 | PTGS2 (0.68) | PTGS2 | |
| SCHEMBL462723 | 0.83 | PTGS2 (0.69) | PTGS2 | |
| SCHEMBL15052403 | 0.83 | PTGS2 (0.69) | PTGS2 | |
| SCHEMBL15072592 | 0.82 | PTGS2 (0.70) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614050-B1 | 1,5-DIARYL-2-ALKYLPYRROLE-3-SUBSTITUTED NITRO ESTERS, SELECTIVE COX-2 INHIBITORS AND NITRIC OXIDE DONORS | Rottapharm Biotech Srl (IT) | 2016-01-20 | — | — | EP | disclosed |