Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 11/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1744606 | 0.88 | LGALS8 (0.50) | — | |
| SCHEMBL1742888 | 0.85 | KAT6A (0.48) | — | |
| SCHEMBL30313850 | 0.77 | BCL2 (0.58) | — | |
| SCHEMBL1742889 | 0.74 | GPBAR1 (0.44) | BRAFMEN1KMT2A | |
| SCHEMBL30313994 | 0.74 | BCL2 (0.61) | — | |
| SCHEMBL30313809 | 0.73 | BCL2 (0.58) | — | |
| SCHEMBL4115298 | 0.72 | CTNNB1 (0.48) | KMT2A | |
| SCHEMBL30752404 | 0.72 | CTNNB1 (0.48) | KMT2A | |
| SCHEMBL8869584 | 0.72 | TTBK1 (0.49) | IDH1ESR1 | |
| SCHEMBL2730313 | 0.71 | BCL2 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2387560-A2 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | Abbott Laboratories (US) | 2011-11-23 | — | — | EP | claimed |
| US-8042193-B1 | Systems and methods for controlling data access by use of a universal anonymous identifier | Albright Associates (US) | 2011-10-18 | — | — | US | claimed |
| WO-2010083441-A2 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2010-07-22 | — | — | WO | claimed |