Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 13/20 | 0.77 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.50 |
| ▸ | AR | P10275 | 4/20 | 0.50 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | ESRRG | P62508 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL544510 | 0.92 | ESR1 (0.61) | ESR1ESR2ARKLF10ALOX15 | |
| SCHEMBL29372911 | 0.92 | ESR1 (0.61) | ESR1ESR2ARKLF10ALOX15 | |
| SCHEMBL13416167 | 0.92 | ESR1 (0.65) | ESR1ESR2ARKLF10ALOX15 | |
| SCHEMBL4462227 | 0.90 | ESR1 (0.59) | ESR1ESR2ARKLF10ALOX15 | |
| SCHEMBL29360146 | 0.88 | ESR1 (1.00) | ESR1ESR2ARKLF10ALOX15 | |
| SCHEMBL35285 | 0.88 | ESR1 (1.00) | ESR1ESR2ARKLF10ALOX15 | |
| SCHEMBL29350788 | 0.88 | ESR1 (1.00) | ESR1ESR2ARKLF10ALOX15 | |
| SCHEMBL12299313 | 0.87 | ESR1 (0.59) | ESR1ESR2ARKLF10ALOX15 | |
| SCHEMBL29696084 | 0.86 | ESR1 (0.95) | ESR1ESR2ARKLF10ALOX15 | |
| SCHEMBL298974 | 0.86 | ESR1 (0.95) | ESR1ESR2ARKLF10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160024300-A1 | POLYMERS AND POLYMER BLENDS WITH ENHANCED GLOSS LEVEL | COVESTRO LLC | 2016-01-28 | — | — | US | disclosed |