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Sugi Predict / Compounds / SCHEMBL298974

SCHEMBL298974

SCHEMBL298974

Cc1cc(C(C)(C)c2ccc(C(C)(C)c3ccc(O)c(C)c3)cc2)ccc1O

nearest known ligand 0.95

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ESR1 P03372 13/20 0.95
▸ ESR2 Q92731 10/20 0.59
▸ AR P10275 4/20 0.59
▸ KLF10 Q13118 1/20 0.55
▸ HPGD P15428 2/20 0.54
▸ HSD17B10 Q99714 2/20 0.54
▸ CYP3A4 P08684 2/20 0.54
▸ TSHR P16473 1/20 0.54
▸ SLC6A2 P23975 1/20 0.54
▸ SLC6A4 P31645 1/20 0.54
▸ HTR6 P50406 1/20 0.54
▸ ESRRG P62508 1/20 0.54
▸ SLC6A3 Q01959 1/20 0.54
▸ TDP1 Q9NUW8 2/20 0.52
▸ TP53 P04637 1/20 0.52
▸ ALOX15 P16050 2/20 0.52
▸ ALOX12 P18054 1/20 0.52
▸ RORC P51449 1/20 0.50
▸ ALDH1A1 P00352 2/20 0.48
▸ PDE10A Q9Y233 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29696084 1.00 ESR1 (0.95) ESR1ESR2ARKLF10HPGD
SCHEMBL35285 0.98 ESR1 (1.00) ESR1ESR2ARKLF10HPGD
SCHEMBL29350788 0.98 ESR1 (1.00) ESR1ESR2ARKLF10HPGD
SCHEMBL29360146 0.98 ESR1 (1.00) ESR1ESR2ARKLF10HPGD
Bisphenol A SCHEMBL16581553 0.94 ESR1 (0.83) ESR1ESR2ARKLF10HPGD
SCHEMBL13799687 0.94 ESR1 (0.83) ESR1ESR2ARKLF10HPGD
SCHEMBL19204944 0.94 ESR1 (0.83) ESR1ESR2ARKLF10HPGD
SCHEMBL1862016 0.94 ESR1 (0.83) ESR1ESR2ARKLF10HPGD
SCHEMBL29473780 0.94 ESR1 (0.83) ESR1ESR2ARKLF10HPGD
SCHEMBL3913903 0.93 ESR1 (0.91) ESR1ESR2ARKLF10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 369 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090163692-A1 AROMATIC POLYETHERS GENERAL ELECTRIC COMPANY (US) 2009-06-25 — — US claimed
US-7375178-B2 High refractive index thermoplastic polyphosphonates ESSILOR INTERNATIONAL (FR) 2008-05-20 — — US claimed
EP-1504048-B1 METHOD OF PREPARING POLYESTERCARBONATES GEN ELECTRIC (US) 2007-11-21 — — EP claimed
US-20070155951-A1 High refractive index thermoplastic polyphosphonates VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY 2007-07-05 — — US claimed
US-7109274-B2 Polyarylate compositions GENERAL ELECTRIC COMPANY (US) 2006-09-19 — — US claimed
EP-1543061-B1 METHOD OF PREPARING TRANSPARENT SILICONE-CONTAINING COPOLYCARBONATES GEN ELECTRIC (US) 2006-08-30 — — EP claimed
US-20060004152-A1 Polyarylate compositions GENERAL ELECTRIC COMPANY 2006-01-05 — — US claimed
US-20050101755-A1 HIGH REFRACTIVE INDEX THERMOPLASTIC POLYPHOSPHONATES JOHNSON & JOHNSON VISION CARE, INC. 2005-05-12 — — US claimed
US-6833422-B2 Interfacial polymerization of polycarbonates with polysiloxanes, then endcapping to form haze-free polycarbonatepolysiloxane copolymers GENERAL ELECTRIC COMPANY 2004-12-21 — — US claimed
US-6780961-B2 CONVERTING OLIGOMERIC CHLOROFORMATES TO HIGH MOLECULAR WEIGHT POLYCARBONATE GENERAL ELECTRIC COMPANY 2004-08-24 — — US claimed
US-20040077820-A1 Method of making polycarbonate GENERAL ELECTRIC COMPANY 2004-04-22 — — US claimed
US-20040039145-A1 Method of preparing transparent silicone-containing copolycarbonates GENERAL ELECTRIC COMPANY 2004-02-26 — — US claimed
US-6657038-B1 Melt condensation copolymerization of dihydroxyaromatic compounds and diphenyl carbonate derivative in presence of metal hydroxide and quaternary phosphonium salt GENERAL ELECTRIC COMPANY 2003-12-02 — — US claimed
US-6600004-B1 Preparing polyestercarbonates is presented in which a mixture of at least one activated diaryl carbonate is reacted under melt polymerization conditions with at least one aromatic dihydroxy compound together with at least one dicarboxylic GENERAL ELECTRIC COMPANY 2003-07-29 — — US claimed
US-20020058779-A1 High refractive index thermoplastic polyphosphonates JOHNSON & JOHNSON VISION PRODUCTS, INC., AND VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. 2002-05-16 — — US claimed
US-6248859-B1 CONTAINING SPIROBIINDANE UNITS; OPTICAL DATA STORAGE MEDIA GENERAL ELECTRIC COMPANY 2001-06-19 — — US claimed
US-12509549-B2 Resin composition for laser direct structuring, molded article, and, method for manufacturing plated molded article MITSUBISHI CHEMICAL CORPORATION (JP) 2025-12-30 — — US disclosed
US-12139578-B2 Cover for millimeter-wave radar and millimeter-wave radar module including the same MITSUBISHI CHEMICAL CORPORATION (JP) 2024-11-12 — — US disclosed
US-4959438-A Epoxy resin composition and prepreg for composite materials using the same from bi and tri-epoxides, triarylbisphenols and diaminodiphenylsulfones MITSUBISHI RAYON COMPANY, LTD. (JP) 1990-09-25 — — US disclosed
EP-0326177-A2 Epoxy resin composition and prepreg for composite materials using the same MITSUBISHI RAYON COMPANY, LTD. (JP) 1989-08-02 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509549-B2 Resin composition for laser direct structuring, molded article, and, method for manufacturing plated molded article MECP2, POT1, EMG1 ESR1 2818/4885ESR2 2603/4885AR 3699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.