Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17470407 | 1.00 | NPC1 (0.50) | NPC1RAB9AAKR1C3MAPTTP53 | |
| SCHEMBL31406274 | 0.86 | NPC1 (0.42) | NPC1RAB9AALDH1A1KMT2AHPGD | |
| SCHEMBL15218724 | 0.86 | NPC1 (0.42) | NPC1RAB9AALDH1A1KMT2AHPGD | |
| SCHEMBL15205392 | 0.86 | NPC1 (0.42) | NPC1RAB9AALDH1A1KMT2AHPGD | |
| SCHEMBL18327180 | 0.85 | NPC1 (0.39) | NPC1RAB9AMAPTTP53LMNA | |
| SCHEMBL28460372 | 0.85 | NPC1 (0.39) | NPC1RAB9AMAPTTP53LMNA | |
| SCHEMBL27007729 | 0.85 | FLT1 (0.38) | NPC1RAB9AMAPTMAPK1ALDH1A1 | |
| SCHEMBL27129876 | 0.85 | FLT1 (0.38) | NPC1RAB9AMAPTMAPK1ALDH1A1 | |
| SCHEMBL18254457 | 0.83 | RXFP1 (0.41) | NPC1RAB9AMAPTLMNAALDH1A1 | |
| SCHEMBL28466910 | 0.83 | RXFP1 (0.41) | NPC1RAB9AMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160028027-A1 | Organometallic Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2016-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160028027-A1 | Organometallic Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device | TTI2, INTS9, LAGE3 | NPC1 4499/4885RAB9A 3100/4885AKR1C3 4577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.