Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | PRCP | P42785 | 4/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2275422 | 0.79 | HTR2A (0.50) | GID4RECQLPRCPHTR2AHTR2C | |
| SCHEMBL8367481 | 0.79 | HTR2A (0.43) | GID4RECQLPRCPHTR2AHTR2C | |
| SCHEMBL8212470 | 0.78 | CHRNA7 (0.49) | GID4PRCPHTR2APDPK1 | |
| SCHEMBL3976186 | 0.77 | CHRNA7 (0.43) | HTR2APDPK1 | |
| SCHEMBL4127623 | 0.76 | ANPEP (0.50) | RECQLPRCPHTR2AHTR2CHTR2B | |
| SCHEMBL4117416 | 0.76 | ANPEP (0.50) | RECQLPRCPHTR2AHTR2CHTR2B | |
| SCHEMBL4108357 | 0.76 | ANPEP (0.50) | RECQLPRCPHTR2AHTR2CHTR2B | |
| SCHEMBL7772712 | 0.75 | PRCP (0.42) | GID4RECQLPRCPHTR2AHTR2C | |
| SCHEMBL14178994 | 0.75 | PDPK1 (0.45) | GID4RECQLPRCPHTR2AHTR2C | |
| SCHEMBL9732856 | 0.73 | GAA (0.67) | RECQLPRCPHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9382209-B2 | Polymorphic forms of ivabradine hydrochloride | CADILA HEALTHCARE LIMITED (IN) | 2016-07-05 | — | — | US | disclosed |
| US-20160024015-A1 | POLYMORPHIC FORMS OF IVABRADINE HYDROCHLORIDE | CADILA HEALTHCARE LIMITED (IN) | 2016-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024015-A1 | POLYMORPHIC FORMS OF IVABRADINE HYDROCHLORIDE | CYP4F3, CYP4F2, SCN5A | GID4 209/4885RECQL 379/4885PRCP 2373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.