Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 1/20 | 0.44 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.42 |
| ▸ | PRCP | P42785 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12066332 | 0.86 | HTR2A (0.52) | HTR2A | |
| SCHEMBL3976186 | 0.86 | CHRNA7 (0.43) | CHRNA7CYP3A4CYP2D6HIF1ACHRNB2 | |
| SCHEMBL16866691 | 0.82 | HTR2A (0.47) | CHRNA7CYP3A4CYP2D6HIF1ACHRNB2 | |
| SCHEMBL434315 | 0.81 | CHRNA7 (0.56) | CHRNA7CYP3A4CYP2D6HIF1ACHRNB2 | |
| SCHEMBL19766703 | 0.80 | CA1 (0.38) | RETHTR2A | |
| SCHEMBL21192353 | 0.80 | CA1 (0.38) | RETHTR2A | |
| SCHEMBL17457429 | 0.78 | GID4 (0.44) | HTR2APDPK1GID4PRCP | |
| SCHEMBL16242005 | 0.77 | RET (0.47) | CHRNA7CYP3A4CYP2D6HIF1ACHRNB2 | |
| SCHEMBL13412792 | 0.77 | CYP3A4 (0.53) | CHRNA7CYP3A4CYP2D6HIF1ACHRNB2 | |
| SCHEMBL13447594 | 0.77 | HTR2A (0.47) | CHRNA7CYP3A4CYP2D6HIF1ACHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008022006-A2 | ARYLALKOXYL HEPATITIS C VIRUS PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |