Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 9/20 | 0.69 |
| ▸ | ABCC1 | P33527 | 8/20 | 0.69 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.69 |
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17457465 | 1.00 | ABCB1 (0.69) | ABCB1ABCC1KCNMA1CRHBPCRHR2 | |
| SCHEMBL2645986 | 0.88 | ABCB1 (0.66) | ABCB1ABCC1KCNMA1CRHBPCRHR2 | |
| SCHEMBL25214665 | 0.88 | ABCC1 (0.55) | ABCB1ABCC1KCNMA1HCAR3MAPK1 | |
| SCHEMBL7467332 | 0.87 | ABCB1 (0.55) | ABCB1ABCC1KCNMA1HCAR3ALDH1A1 | |
| SCHEMBL22439814 | 0.85 | ABCB1 (0.68) | ABCB1ABCC1KCNMA1NPC1MAPK1 | |
| SCHEMBL7466534 | 0.85 | ABCB1 (0.64) | ABCB1ABCC1KCNMA1NPC1MAPT | |
| SCHEMBL7462935 | 0.84 | ABCB1 (0.52) | ABCB1ABCC1KCNMA1HCAR3RAB9A | |
| SCHEMBL2466950 | 0.84 | ABCB1 (0.52) | ABCB1ABCC1KCNMA1HCAR3APP | |
| SCHEMBL29007522 | 0.84 | ABCC1 (0.62) | ABCB1ABCC1KCNMA1CRHBPCRHR2 | |
| SCHEMBL6587509 | 0.82 | ABCC1 (0.59) | ABCB1ABCC1KCNMA1CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970107-B1 | PHOTOSWITCHABLE HDAC INHIBITORS | MASSACHUSETTS GEN HOSPITAL (US) | 2023-11-15 | — | — | EP | disclosed |
| US-11596691-B2 | Photoswitchable HDAC inhibitors | THE GENERAL HOSPITAL CORPORATION (US) | 2023-03-07 | — | — | US | disclosed |
| US-20210162048-A1 | Photoswitchable HDAC Inhibitors | THE GENERAL HOSPITAL CORPORATION | 2021-06-03 | — | — | US | disclosed |
| US-10828367-B2 | Photoswitchable HDAC inhibitors | THE GENERAL HOSPITAL CORPORATION (US) | 2020-11-10 | — | — | US | disclosed |
| US-20190070295-A1 | Photoswitchable HDAC Inhibitors | THE GENERAL HOSPITAL CORPORATION | 2019-03-07 | — | — | US | disclosed |
| US-9981038-B2 | Photoswitchable HDAC inhibitors | THE GENERAL HOSPITAL CORPORATION (US) | 2018-05-29 | — | — | US | disclosed |
| US-20160022817-A1 | Photoswitchable HDAC Inhibitors | THE GENERAL HOSPITAL CORPORATION (US) | 2016-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190070295-A1 | Photoswitchable HDAC Inhibitors | HDAC4, HDAC1, HDAC3 | ABCB1 4084/4885ABCC1 4252/4885KCNMA1 3294/4885 |
| US-20160022817-A1 | Photoswitchable HDAC Inhibitors | HDAC1, HDAC4, HDAC3 | ABCB1 4500/4885ABCC1 4528/4885KCNMA1 3220/4885 |
| US-20210162048-A1 | Photoswitchable HDAC Inhibitors | HDAC4, HDAC1, HDAC3 | ABCB1 4084/4885ABCC1 4252/4885KCNMA1 3294/4885 |
| US-11596691-B2 | Photoswitchable HDAC inhibitors | HDAC4, HDAC1, HDAC3 | ABCB1 4084/4885ABCC1 4252/4885KCNMA1 3294/4885 |
| US-10828367-B2 | Photoswitchable HDAC inhibitors | HDAC4, HDAC1, HDAC3 | ABCB1 4084/4885ABCC1 4252/4885KCNMA1 3294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.