SCHEMBL1745798

SCHEMBL1745798

NC(=O)Nc1ccccc1[N+](=O)[O-]

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.71
MEN1 O00255 1/20 0.71
KCNMA1 Q12791 1/20 0.61
PHGDH O43175 1/20 0.59
RAB9A P51151 3/20 0.58
GAA P10253 2/20 0.58
CYP3A4 P08684 1/20 0.58
CYP2C9 P11712 1/20 0.58
CYP2C19 P33261 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
TP53 P04637 1/20 0.57
NPC1 O15118 3/20 0.56
MAPT P10636 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
PDK1 Q15118 1/20 0.56
PDK2 Q15119 1/20 0.56
PDK3 Q15120 1/20 0.56
PDK4 Q16654 1/20 0.56
ALDH1A1 P00352 2/20 0.55
POLB P06746 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30388225 1.00 KMT2A (0.71) KMT2AMEN1KCNMA1PHGDHRAB9A
SCHEMBL28426188 0.87 KMT2A (0.65) KMT2AMEN1KCNMA1PHGDHRAB9A
SCHEMBL11332310 0.86 KMT2A (0.73) KMT2AMEN1KCNMA1PHGDHRAB9A
SCHEMBL6857920 0.86 KMT2A (0.73) KMT2AMEN1KCNMA1PHGDHRAB9A
SCHEMBL6205171 0.86 KMT2A (0.54) KMT2AMEN1KCNMA1PHGDHRAB9A
SCHEMBL11582018 0.85 KMT2A (0.58) KMT2AMEN1KCNMA1PHGDHRAB9A
SCHEMBL4905868 0.85 KMT2A (0.62) KMT2AMEN1KCNMA1PHGDHRAB9A
SCHEMBL1883671 0.85 MEN1 (0.62) KMT2AMEN1KCNMA1PHGDHRAB9A
SCHEMBL29838526 0.85 MEN1 (0.62) KMT2AMEN1KCNMA1PHGDHRAB9A
SCHEMBL113558 0.85 MEN1 (0.71) KMT2AMEN1KCNMA1PHGDHRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3555189-A1 REPAIRABLE POLYMER COMPOSITIONS Gnosys Global Limited (GB) 2019-10-23 EP claimed
WO-2018109487-A1 REPAIRABLE POLYMER COMPOSITIONS THE UNIVERSITY OF READING (GB) 2018-06-21 WO claimed
CN-103221388-A Novel sulfonamide compounds for inhibition of metastatic tumor growth METASIGNAL THERAPEUTICS INC 2013-07-24 CN claimed
CN-102796091-A Substituted oxazolidinone compound and preparation method and application thereof UNIV PEKING FOUNDER GROUP CO 2012-11-28 CN claimed
US-7539006-B2 Electrolytic solution for driving electrolytic capacitor and electrolytic capacitor RUBYCON CORPORATION (JP) 2009-05-26 US claimed
US-20070029529-A1 Electrolytic solution for driving electrolytic capacitor and electrolytic capacitor KOMATSU AKIHIKO 2007-02-08 US claimed
US-20040245105-A1 Electrolyte solution for driving electrolytic capacitor and electrolytic capacitor RUBYCON CORPORATION (JP) 2004-12-09 US claimed
EP-1437749-A1 ELECTROLYTE SOLUTION FOR DRIVING ELECTROLYTIC CAPACITOR AND ELECTROLYTIC CAPACITOR Rubycon Corporation (JP) 2004-07-14 EP claimed
CN-1270592-A Spiroazabicyclic heterocyclic compounds ASTRA AB (SE) 2000-10-18 CN claimed
CN-1157617-A Heterobicyclic derivatives FUJISAWA PHARMACEUTICAL CO (JP) 1997-08-20 CN claimed
EP-0235878-A2 Novel compounds BEECHAM GROUP PLC (GB) 1987-09-09 EP claimed
EP-3555189-A1 REPAIRABLE POLYMER COMPOSITIONS Gnosys Global Limited (GB) 2019-10-23 EP disclosed
WO-2018109487-A1 REPAIRABLE POLYMER COMPOSITIONS THE UNIVERSITY OF READING (GB) 2018-06-21 WO disclosed
EP-2755651-A1 COMPOSITIONS AND METHODS FOR TREATING METABOLIC DISORDERS Biomed Valley Discoveries, Inc. (US) 2014-07-23 EP disclosed
CN-103221388-A Novel sulfonamide compounds for inhibition of metastatic tumor growth METASIGNAL THERAPEUTICS INC 2013-07-24 CN disclosed
WO-1992017466-A1 NOVEL QUINOLONES, METHOD OF PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM BOUCHARA S.A. (FR) 1992-10-15 WO disclosed
WO-1992015574-A1 NOVEL QUINOLONES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME BOUCHARA S.A. (FR) 1992-09-17 WO disclosed
WO-1992005170-A1 INDOLE UREAS AS 5 HT RECEPTOR ANTAGONIST BEECHAM GROUP PLC (GB) 1992-04-02 WO disclosed
US-4316861-A N-Nitroaryl-N-halosulfonyl ureas HOECHST AKTIENGESELLSCHAFT (DE) 1982-02-23 US disclosed
US-4206212-A Combating plant pathogenic bacteria with 3-halogeno-benzotriazine 1-oxides BAYER AKTIENGESELLSCHAFT (DE) 1980-06-03 US disclosed