Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.54 |
| ▸ | PHGDH | O43175 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29838526 | 1.00 | MEN1 (0.62) | MEN1KMT2AMAPTRAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL8764180 | 0.98 | MEN1 (0.60) | MEN1KMT2AMAPTRAB9ANPC1 | |
| Aziridine SCHEMBL29221601 | 0.92 | MAPT (0.55) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL28994142 | 0.91 | MAPT (0.53) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL11166479 | 0.87 | MAPT (0.49) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL1745798 | 0.85 | KMT2A (0.71) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL30388225 | 0.85 | KMT2A (0.71) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL2937028 | 0.83 | ALDH1A1 (0.68) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL15347550 | 0.83 | MAPT (0.62) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL5147740 | 0.82 | KMT2A (0.62) | MEN1KMT2AMAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894909-B | Polyethylenimine nitrophenyl thiourea probe, preparation method and application thereof in recognition of anions | 新疆大学 | 2024-06-04 | — | — | CN | claimed |
| CN-115894909-A | Polyethyleneimine nitrophenyl thiourea probe, preparation method and application thereof in anion recognition | 新疆大学 | 2023-04-04 | — | — | CN | claimed |
| EP-1611109-A4 | NOVEL QUINAZOLINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO LTD (JP) | 2009-06-24 | — | — | EP | claimed |
| JP-2006522109-A | — | — | 2006-09-28 | — | — | JP | claimed |
| EP-1611109-A1 | NOVEL QUINAZOLINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2006-01-04 | — | — | EP | claimed |
| WO-2004087680-A1 | NOVEL QUINAZOLINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2004-10-14 | — | — | WO | claimed |
| US-5684156-A | Process for preparation of clonidine derivatives | ALCON RESEARCH, LTD. | 1997-11-04 | — | — | US | claimed |
| EP-0693055-B1 | NOVEL PROCESS FOR PREPARATION OF CLONIDINE DERIVATIVES | ALCON LAB INC (US) | 1997-05-21 | — | — | EP | claimed |
| EP-0693055-A1 | NOVEL PROCESS FOR PREPARATION OF CLONIDINE DERIVATIVES | ALCON LAB INC (US) | 1996-01-24 | — | — | EP | claimed |
| WO-1995021818-A1 | NOVEL PROCESS FOR PREPARATION OF CLONIDINE DERIVATIVES | ALCON LABORATORIES, INC. (US) | 1995-08-17 | — | — | WO | claimed |
| CN-115894909-B | Polyethylenimine nitrophenyl thiourea probe, preparation method and application thereof in recognition of anions | 新疆大学 | 2024-06-04 | — | — | CN | disclosed |
| CN-115894909-B | Polyethylenimine nitrophenyl thiourea probe, preparation method and application thereof in recognition of anions | 新疆大学 | 2024-06-04 | — | — | CN | disclosed |
| CN-115894909-B | Polyethylenimine nitrophenyl thiourea probe, preparation method and application thereof in recognition of anions | 新疆大学 | 2024-06-04 | — | — | CN | disclosed |
| US-20230129765-A1 | METHOD FOR PRODUCING POLYTHIOETHER COMPOUND | DAICEL CORPORATION (JP) | 2023-04-27 | — | — | US | disclosed |
| CN-115894909-A | Polyethyleneimine nitrophenyl thiourea probe, preparation method and application thereof in anion recognition | 新疆大学 | 2023-04-04 | — | — | CN | disclosed |
| EP-0625972-B1 | PROCESS FOR THE PREPARATION OF 2-AMINO-7-NITROBENZOTHIAZOLES | RHONE POULENC RORER SA (FR) | 1996-03-13 | — | — | EP | disclosed |
| EP-0693055-A1 | NOVEL PROCESS FOR PREPARATION OF CLONIDINE DERIVATIVES | ALCON LAB INC (US) | 1996-01-24 | — | — | EP | disclosed |
| WO-1995021818-A1 | NOVEL PROCESS FOR PREPARATION OF CLONIDINE DERIVATIVES | ALCON LABORATORIES, INC. (US) | 1995-08-17 | — | — | WO | disclosed |
| EP-0625972-A1 | PROCESS FOR THE PREPARATION OF 2-AMINO 7-NITRO BENZOTHIAZOLES. | RHONE POULENC RORER SA (FR) | 1994-11-30 | — | — | EP | disclosed |
| WO-1993012099-A1 | PROCESS FOR THE PREPARATION OF 2-AMINO 7-NITRO BENZOTHIAZOLES | RHONE-POULENC RORER S.A. (FR) | 1993-06-24 | — | — | WO | disclosed |