Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 8/20 | 0.44 |
| ▸ | NPC1 | O15118 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17466584 | 1.00 | MAPT (0.57) | MAPTALDH1A1LMNAKMT2AMAPK1 | |
| SCHEMBL16094850 | 1.00 | MAPT (0.57) | MAPTALDH1A1LMNAKMT2AMAPK1 | |
| SCHEMBL14782263 | 0.86 | MEN1 (0.45) | MAPTALDH1A1LMNAKMT2AMAPK1 | |
| SCHEMBL14782161 | 0.86 | MEN1 (0.45) | MAPTALDH1A1LMNAKMT2AMAPK1 | |
| SCHEMBL14947933 | 0.86 | MEN1 (0.45) | MAPTALDH1A1LMNAKMT2AMAPK1 | |
| SCHEMBL16956015 | 0.78 | MAPT (0.61) | MAPTALDH1A1LMNAKMT2AMAPK1 | |
| SCHEMBL6677275 | 0.77 | MAPT (0.73) | MAPTALDH1A1LMNAKMT2AMAPK1 | |
| SCHEMBL11819120 | 0.76 | MAPT (0.67) | MAPTALDH1A1LMNAKMT2AMAPK1 | |
| SCHEMBL16950814 | 0.76 | MAPT (0.58) | MAPTALDH1A1LMNAKMT2AMAPK1 | |
| SCHEMBL13900800 | 0.75 | MAPT (0.55) | MAPTALDH1A1LMNAKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160024573-A1 | PHOTOCLEAVABLE DEOXYNUCLEOTIDES WITH HIGH-RESOLUTION CONTROL OF DEPROTECTION KINETICS | IBIS BIOSCIENCES, INC. | 2016-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024573-A1 | PHOTOCLEAVABLE DEOXYNUCLEOTIDES WITH HIGH-RESOLUTION CONTROL OF DEPROTECTION KINETICS | UNG, POLN, POLL | MAPT 2433/4885ALDH1A1 2104/4885LMNA 573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.