Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16950814 | 0.85 | MAPT (0.58) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL16958210 | 0.84 | ALDH1A1 (0.47) | MAPTALDH1A1LMNAMAPK1HPGD | |
| SCHEMBL16962262 | 0.84 | MAPT (0.61) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL6677275 | 0.80 | MAPT (0.73) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL16955293 | 0.80 | MAPT (0.67) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL16961595 | 0.79 | TXNRD1 (0.40) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL17458659 | 0.78 | MAPT (0.57) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL16094850 | 0.78 | MAPT (0.57) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL17466584 | 0.78 | MAPT (0.57) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL22291692 | 0.78 | MAPT (0.69) | MAPTALDH1A1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |