SCHEMBL174587

SCHEMBL174587

C=CC([O])O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12055831 0.73
SCHEMBL12054896 0.73
SCHEMBL515409 0.73
SCHEMBL30980 0.70
SCHEMBL465399 0.70
SCHEMBL4251744 0.70
SCHEMBL9019444 0.68
Bicarbonate SCHEMBL6361730 0.67
SCHEMBL874970 0.67 LMNA (0.35)
SCHEMBL3416266 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112533612-A Bone-targeting antimicrobial oxazolidinone-related compounds, formulations thereof, and uses thereof 弗兰克·哈洛克·埃比蒂诺 2021-03-19 CN claimed
EP-2430022-B1 1,2,4-Triazolo[4,3-a]pyridine derivatives and their use for the treatment or prevention of neurological and psychiatric disorders JANSSEN PHARMACEUTICALS INC (US) 2013-11-20 EP claimed
EP-2298769-B1 Xanthin derivatives, their production and utilisation as medicine BOEHRINGER INGELHEIM PHARMA (DE) 2013-10-30 EP claimed
EP-1953162-B9 Xanthin derivatives, their production and utilisation as medicine BOEHRINGER INGELHEIM PHARMA (DE) 2012-10-31 EP claimed
EP-1953162-B1 Xanthin derivatives, their production and utilisation as medicine BOEHRINGER INGELHEIM PHARMA (DE) 2012-06-20 EP claimed
JP-4809228-B2 2011-11-09 JP claimed
US-20110269758-A1 NAPHTHYRIDINONES AS PROTEIN KINASE INHIBITORS MERCK PATENT GMBH (DE) 2011-11-03 US claimed
EP-2245014-B1 UREA DERIVATIVES OF BENZOMORPHANES AND RELATED SCAFFOLDS, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE BOEHRINGER INGELHEIM INT (DE) 2011-11-02 EP claimed
JP-2011526912-A 2011-10-20 JP claimed
JP-4725946-B2 2011-07-13 JP claimed
CN-1088043-C Demulsification type organic flocculant and preparation process thereof CHINA PETROCHEMICAL CORP (CN) 2002-07-24 CN claimed
US-20020081275-A1 Heterogeneous reaction method for preparing functionalized polyanilines NATIONAL TSING HUA UNIVERSITY (TW) 2002-06-27 US claimed
WO-2001064246-A2 FARNESYL PROTEIN TRANSFERASE INHIBITOR COMBINATIONS WITH AN HER2 ANTIBODY JANSSEN PHARMACEUTICA N.V. (BE) 2001-09-07 WO claimed
CN-1257044-A Demulsification type organic flocculant and preparation process thereof CHINA PETROCHEMICAL CORP (CN) 2000-06-21 CN claimed
EP-0521827-B1 Pharmacological active hydrazin derivatives and process for their preparation CIBA GEIGY AG (CH) 1996-09-25 EP claimed
EP-0154793-B1 1-OXADETHIACEPHALOSPORIN DERIVATIVES AND PROCESSES FOR THEIR PREPARATION BAYER AG (DE) 1988-08-31 EP claimed
EP-0144032-B1 CEPHALOSPORINS AND PROCESS FOR THEIR PREPARATION BAYER AG (DE) 1988-08-03 EP claimed
EP-0266897-A1 Synthesis of alkylsulfinyl substituted 2-phenylimidazo [4,5-c] pyridines ELI LILLY AND COMPANY (US) 1988-05-11 EP claimed
US-4163730-A Hydroxyalkyl hydroxy-aromatic condensation products as lubricant additives THE LUBRIZOL CORPORATION (US) 1979-08-07 US claimed
US-4108784-A Hydroxyalkyl hydroxy-aromatic condensation products as fuel and lubricant additives THE LUBRIZOL CORPORATION (US) 1978-08-22 US claimed