SCHEMBL17459231

SCHEMBL17459231

CCCCCCCCCCCCCC(=O)O[C@@H](C=O)[C@@H](OS(=O)(=O)O)[C@@H](O)[C@H](O)CO

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.45
MAPK1 P28482 1/20 0.45
PRKCA P17252 5/20 0.40
LMNA P02545 4/20 0.40
PRKCE Q02156 2/20 0.40
PRKCQ Q04759 2/20 0.40
PRKCD Q05655 2/20 0.40
KDM4E B2RXH2 1/20 0.39
DUSP3 P51452 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
DGKA P23743 1/20 0.38
ALDH1A1 P00352 2/20 0.37
FAAH O00519 1/20 0.36
HPGD P15428 1/20 0.36
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11506064 0.90 MAPT (0.51) MAPTMAPK1PRKCALMNAPRKCE
SCHEMBL8201074 0.90 MAPT (0.51) MAPTMAPK1PRKCALMNAPRKCE
SCHEMBL8179685 0.90 MAPT (0.51) MAPTMAPK1PRKCALMNAPRKCE
SCHEMBL17628561 0.84 MAPT (0.55) MAPTMAPK1PRKCALMNAPRKCE
SCHEMBL9228545 0.84 MAPT (0.55) MAPTMAPK1PRKCALMNAPRKCE
SCHEMBL17628557 0.84 MAPT (0.55) MAPTMAPK1PRKCALMNAPRKCE
SCHEMBL1899724 0.83 MAPT (0.49) MAPTMAPK1PRKCALMNAPRKCE
SCHEMBL2563584 0.83 MAPT (0.49) MAPTMAPK1PRKCALMNAPRKCE
SCHEMBL5355667 0.83 MAPT (0.49) MAPTMAPK1PRKCALMNAPRKCE
SCHEMBL15463455 0.82 MAPT (0.54) MAPTMAPK1PRKCALMNAPRKCE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3193923-B1 ADJUVANTS LITEVAX B V (NL) 2019-09-18 EP disclosed
US-10342867-B2 Adjuvants LITEVAX B.V. (NL) 2019-07-09 US disclosed
US-20170209568-A1 ADJUVANTS LITEVAX B.V. (NL) 2017-07-27 US disclosed
EP-3193923-A1 ADJUVANTS Litevax B.V. (NL) 2017-07-26 EP disclosed
WO-2016013938-A1 ADJUVANTS LITEVAX B.V. (NL) 2016-01-28 WO disclosed