SCHEMBL8201074

SCHEMBL8201074

CCCCCCCCCCCCCCCC(=O)O[C@@H]([C@H](O)[C@H](O)CO)[C@H](C=O)OC(=O)CCCCCCCCCCCCCCC

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.51
MAPK1 P28482 1/20 0.51
LMNA P02545 4/20 0.46
PRKCA P17252 5/20 0.46
PRKCE Q02156 2/20 0.46
PRKCQ Q04759 2/20 0.46
PRKCD Q05655 2/20 0.46
KDM4E B2RXH2 1/20 0.44
DUSP3 P51452 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
ALDH1A1 P00352 2/20 0.42
DGKA P23743 1/20 0.42
FAAH O00519 1/20 0.40
HPGD P15428 1/20 0.40
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8179685 1.00 MAPT (0.51) MAPTMAPK1LMNAPRKCAPRKCE
SCHEMBL11506064 1.00 MAPT (0.51) MAPTMAPK1LMNAPRKCAPRKCE
SCHEMBL5355667 0.92 MAPT (0.49) MAPTMAPK1LMNAPRKCAPRKCE
SCHEMBL1899724 0.92 MAPT (0.49) MAPTMAPK1LMNAPRKCAPRKCE
SCHEMBL2563584 0.92 MAPT (0.49) MAPTMAPK1LMNAPRKCAPRKCE
SCHEMBL11504093 0.92 MAPT (0.54) MAPTMAPK1LMNAPRKCAPRKCE
SCHEMBL1534016 0.91 MAPT (0.48) MAPTMAPK1LMNAPRKCAPRKCE
SCHEMBL8206291 0.90 MAPT (0.53) MAPTMAPK1LMNAPRKCAPRKCE
SCHEMBL11504208 0.90 MAPT (0.53) MAPTMAPK1LMNAPRKCAPRKCE
SCHEMBL17459231 0.90 MAPT (0.45) MAPTMAPK1LMNAPRKCAPRKCE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6066482-A AMINO ACID SEQUENCES; FOR PRODUCING SUGAR POLYESTERS WITH PEST REPELLENT PROPERTIES USED IN AGRICULTURE, EMULSIFICATION PROPERTIES USED IN FOOD AND COSMETIC INDUSTRIES, AND EMOLLIENT PROPERTIES USED IN COSMETICS CORNELL RESEARCH FOUNDATION, INC. (US) 2000-05-23 US disclosed
EP-0909326-A1 ACYLTRANSFERASE AND GENE ENCODING ACYLTRANSFERASE CORNELL RESEARCH FOUNDATION, INC. (US) 1999-04-21 EP disclosed
US-5756328-A PURE ENZYME WHICH CATALYZES TRANSFER OF ACYL SUBSTITUENTS TO PRODUCE SUGAR ESTERS OR SUGAR POLYESTERS, HAVING SPECIFIED AMINO ACID SEQUENCE CORNELL RESEARCH FOUNDATION, INC. (US) 1998-05-26 US disclosed
WO-1997048811-A1 ACYLTRANSFERASE AND GENE ENCODING ACYLTRANSFERASE CORNELL RESEARCH FOUNDATION, INC. (US) 1997-12-24 WO disclosed