Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | AR | P10275 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.64 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | BCHE | P06276 | 1/20 | 0.60 |
| ▸ | GUSB | P08236 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21647111 | 1.00 | MAPT (1.00) | MAPTMAPK1ARLMNANPC1 | |
| SCHEMBL29837067 | 1.00 | MAPT (1.00) | MAPTMAPK1ARLMNANPC1 | |
| SCHEMBL5576960 | 0.86 | MAPT (0.76) | MAPTMAPK1LMNACYP3A4CYP1B1 | |
| SCHEMBL9250766 | 0.86 | MAPT (0.76) | MAPTMAPK1LMNACYP3A4CYP1B1 | |
| SCHEMBL10893208 | 0.86 | MAPT (0.75) | MAPTMAPK1LMNANPC1CYP3A4 | |
| SCHEMBL626787 | 0.86 | MAPT (0.75) | MAPTMAPK1LMNANPC1CYP3A4 | |
| SCHEMBL29420130 | 0.86 | MAPT (0.75) | MAPTMAPK1LMNANPC1CYP3A4 | |
| SCHEMBL626785 | 0.86 | MAPT (0.75) | MAPTMAPK1LMNANPC1CYP3A4 | |
| SCHEMBL10416123 | 0.85 | MAPT (0.79) | MAPTMAPK1LMNANPC1CYP1A2 | |
| Methane SCHEMBL728022 | 0.84 | MAPT (0.73) | MAPTMAPK1LMNANPC1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114890975-B | Compound with fused ring chroman structure and preparation method thereof | 合肥工业大学 | 2023-07-18 | — | — | CN | claimed |
| CN-114890975-A | Compound with parachroman structure and preparation method thereof | 合肥工业大学 | 2022-08-12 | — | — | CN | claimed |
| CN-114890975-B | Compound with fused ring chroman structure and preparation method thereof | 合肥工业大学 | 2023-07-18 | — | — | CN | disclosed |
| CN-116162079-A | Synthesis method of aminocoumarin compound | 浙江工业大学 | 2023-05-26 | — | — | CN | disclosed |
| CN-114890975-A | Compound with parachroman structure and preparation method thereof | 合肥工业大学 | 2022-08-12 | — | — | CN | disclosed |
| CN-108774207-B | Cyclopenta [ c ] chromene compounds and process for preparing the same | 苏州大学张家港工业技术研究院 | 2021-12-17 | — | — | CN | disclosed |
| WO-2020024099-A1 | CYCLOPENTADIENYL [C] CHROMIUM COMPOUND AND PREPARATION METHOD THEREFOR | 苏州大学张家港工业技术研究院 | 2020-02-06 | — | — | WO | disclosed |
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |