Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | TYR | P14679 | 1/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.67 |
| ▸ | CA1 | P00915 | 1/20 | 0.67 |
| ▸ | CA2 | P00918 | 1/20 | 0.67 |
| ▸ | CA4 | P22748 | 1/20 | 0.67 |
| ▸ | BCHE | P06276 | 3/20 | 0.66 |
| ▸ | GUSB | P08236 | 1/20 | 0.66 |
| ▸ | JUN | P05412 | 1/20 | 0.63 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.63 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.58 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10893208 | 0.98 | MAPT (0.75) | MAPTMAPK1TYRNFKB1CA1 | |
| SCHEMBL626785 | 0.98 | MAPT (0.75) | MAPTMAPK1TYRNFKB1CA1 | |
| SCHEMBL626787 | 0.98 | MAPT (0.75) | MAPTMAPK1TYRNFKB1CA1 | |
| SCHEMBL29420130 | 0.98 | MAPT (0.75) | MAPTMAPK1TYRNFKB1CA1 | |
| Chalcone SCHEMBL28301237 | 0.91 | CYP1B1 (0.73) | MAPTMAPK1TYRNFKB1CA1 | |
| SCHEMBL21647113 | 0.88 | MAPT (0.71) | MAPTMAPK1TYRNFKB1CA1 | |
| SCHEMBL9250766 | 0.87 | MAPT (0.76) | MAPTMAPK1TYRNFKB1CA1 | |
| SCHEMBL5576960 | 0.87 | MAPT (0.76) | MAPTMAPK1TYRNFKB1CA1 | |
| SCHEMBL9006476 | 0.86 | MAPT (0.69) | MAPTMAPK1TYRNFKB1BCHE | |
| SCHEMBL1073514 | 0.86 | IAPP (0.62) | MAPTMAPK1TYRNFKB1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104705565-A | Method for preparing three-high (high blood lipid, high blood pressure and high blood sugar) prevention dietary therapy rice | WANG YUEJIN | 2015-06-17 | — | — | CN | claimed |
| EP-1534314-B1 | A nutritional and therapeutic composition of an insulin sensitizer and a peptide fraction | DSM IP ASSETS BV (NL) | 2014-10-22 | — | — | EP | claimed |
| JP-4719465-B2 | — | — | 2011-07-06 | — | — | JP | claimed |
| US-7648957-B2 | Nutritional and therapeutic composition of an insulin sensitizer and a peptide fraction | DSM IP ASSETS B.V. (NL) | 2010-01-19 | — | — | US | claimed |
| JP-2006502154-A | — | — | 2006-01-19 | — | — | JP | claimed |
| US-20050271744-A1 | Nutritional and therapeutic composition of an insulin sensitizer and a peptide fraction | DSM IP ASSETS B.V. (NL) | 2005-12-08 | — | — | US | claimed |
| US-6903136-B2 | Food supplements containing 4-hydroxyisoleucine and creatine | EXPERIMENTAL AND APPLIED SCIENCES, INC. (US) | 2005-06-07 | — | — | US | claimed |
| EP-1534314-A1 | A NUTRITIONAL AND THERAPEUTIC COMPOSITION OF AN INSULIN SENSITIZER AND A PEPTIDE FRACTION | DSM IP Assets B.V. (NL) | 2005-06-01 | — | — | EP | claimed |
| WO-2004022083-A1 | A NUTRITIONAL AND THERAPEUTIC COMPOSITION OF AN INSULIN SENSITIZER AND A PEPTIDE FRACTION | DSM IP ASSETS B.V. (NL) | 2004-03-18 | — | — | WO | claimed |
| US-20030224062-A1 | Food supplements containing 4-hydroxyisoleucine and creatine | NATIONAL SUPPLEMENT ASSOCIATION, INCORPORATED | 2003-12-04 | — | — | US | claimed |
| WO-2003088947-A1 | FOOD SUPPLEMENTS CONTAINING 4-HYDROXYISOLEUCINE AND CREATINE | EXPERIMENTAL & APPLIED SCIENCES, INC. (US) | 2003-10-30 | — | — | WO | claimed |
| US-20200179308-A1 | USE OF ISOHUMULONES AND DERIVATIVES THEREOF TO TREAT POLYCYSTIC OVARY SYNDROME | KINDEX PHARMACEUTICALS, INC. | 2020-06-11 | — | — | US | disclosed |
| EP-3609862-A1 | USE OF ISOHUMULONES AND DERIVATIVES THEREOF TO TREAT POLYCYSTIC OVARY SYNDROME | Kindex Pharmaceuticals, Inc. (US) | 2020-02-19 | — | — | EP | disclosed |
| EP-3107556-B1 | COMPOSITIONS FOR PREVENTING AND/OR TREATING PATHOLOGICAL CONDITIONS ASSOCIATED WITH ALPHA-GLUCOSIDASE | UNIV LA ROCHELLE (FR) | 2019-04-10 | — | — | EP | disclosed |
| WO-2018191522-A1 | USE OF ISOHUMULONES AND DERIVATIVES THEREOF TO TREAT POLYCYSTIC OVARY SYNDROME | KINDEX THERAPEUTICS, LLC (US) | 2018-10-18 | — | — | WO | disclosed |
| US-6787163-B2 | Therapeutic treatment for blood sugar regulation | HARRIS DENNIS H (US) | 2004-09-07 | — | — | US | disclosed |
| US-20040142045-A1 | THERAPEUTIC TREATMENT FOR BLOOD SUGAR REGULATION | HARRIS DENNIS H (US) | 2004-07-22 | — | — | US | disclosed |
| WO-2004022083-A1 | A NUTRITIONAL AND THERAPEUTIC COMPOSITION OF AN INSULIN SENSITIZER AND A PEPTIDE FRACTION | DSM IP ASSETS B.V. (NL) | 2004-03-18 | — | — | WO | disclosed |
| US-20030224062-A1 | Food supplements containing 4-hydroxyisoleucine and creatine | NATIONAL SUPPLEMENT ASSOCIATION, INCORPORATED | 2003-12-04 | — | — | US | disclosed |
| WO-2003088947-A1 | FOOD SUPPLEMENTS CONTAINING 4-HYDROXYISOLEUCINE AND CREATINE | EXPERIMENTAL & APPLIED SCIENCES, INC. (US) | 2003-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200179308-A1 | USE OF ISOHUMULONES AND DERIVATIVES THEREOF TO TREAT POLYCYSTIC OVARY SYNDROME | PKD1, TKT, CPT1A | MAPT 2919/4885MAPK1 3497/4885TYR 2633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.