Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.68 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.68 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.68 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 10/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL289598 | 0.89 | MEN1 (0.77) | MEN1CYP3A4KMT2ATSHRPDK1 | |
| SCHEMBL3612895 | 0.87 | CYP3A4 (0.78) | MEN1CYP3A4KMT2ATSHRPDK1 | |
| SCHEMBL17470671 | 0.87 | MEN1 (0.74) | MEN1CYP3A4KMT2ATSHRPDK1 | |
| SCHEMBL29353573 | 0.87 | MEN1 (0.74) | MEN1CYP3A4KMT2ATSHRPDK1 | |
| SCHEMBL19174219 | 0.87 | MEN1 (0.74) | MEN1CYP3A4KMT2ATSHRPDK1 | |
| SCHEMBL239240 | 0.87 | MEN1 (0.74) | MEN1CYP3A4KMT2ATSHRPDK1 | |
| SCHEMBL14496633 | 0.84 | TDP1 (0.76) | MEN1CYP3A4KMT2ATSHRPDK1 | |
| SCHEMBL18431217 | 0.84 | TDP1 (0.76) | MEN1CYP3A4KMT2ATSHRPDK1 | |
| SCHEMBL16204336 | 0.83 | MEN1 (0.74) | MEN1CYP3A4KMT2ATSHRPDK1 | |
| SCHEMBL18431216 | 0.83 | MEN1 (0.74) | MEN1CYP3A4KMT2ATSHRPDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3171864-A1 | NANOPARTICLE FORMULATIONS OF LOW-WATER SOLUBILITY ACTIVES | Bend Research, Inc (US) | 2017-05-31 | — | — | EP | disclosed |
| WO-2016012906-A1 | NANOPARTICLE FORMULATIONS OF LOW-WATER SOLUBILITY ACTIVES | BEND RESEARCH, INC. (US) | 2016-01-28 | — | — | WO | disclosed |