Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.78 |
| ▸ | MEN1 | O00255 | 3/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.78 |
| ▸ | TSHR | P16473 | 2/20 | 0.78 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.78 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.78 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.78 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.78 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.78 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.77 |
| ▸ | TP53 | P04637 | 1/20 | 0.77 |
| ▸ | MAPT | P10636 | 1/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.77 |
| ▸ | KARS1 | Q15046 | 2/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | RXRA | P19793 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27863 | 0.88 | CYP3A4 (1.00) | CYP3A4MEN1KMT2ATSHRCYP2D6 | |
| SCHEMBL14029315 | 0.88 | CYP3A4 (1.00) | CYP3A4MEN1KMT2ATSHRCYP2D6 | |
| SCHEMBL29380336 | 0.88 | CYP3A4 (1.00) | CYP3A4MEN1KMT2ATSHRCYP2D6 | |
| SCHEMBL9108470 | 0.88 | CYP3A4 (1.00) | CYP3A4MEN1KMT2ATSHRCYP2D6 | |
| SCHEMBL4943352 | 0.88 | CYP3A4 (1.00) | CYP3A4MEN1KMT2ATSHRCYP2D6 | |
| SCHEMBL31682257 | 0.88 | CYP3A4 (1.00) | CYP3A4MEN1KMT2ATSHRCYP2D6 | |
| SCHEMBL27864 | 0.88 | CYP3A4 (1.00) | CYP3A4MEN1KMT2ATSHRCYP2D6 | |
| SCHEMBL17158674 | 0.88 | CYP3A4 (1.00) | CYP3A4MEN1KMT2ATSHRCYP2D6 | |
| SCHEMBL17459735 | 0.87 | MEN1 (0.68) | CYP3A4MEN1KMT2ATSHRCYP2D6 | |
| Hydrochloric Acid SCHEMBL29409504 | 0.87 | CYP3A4 (1.00) | CYP3A4MEN1KMT2ATSHRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258183-A1 | Compounds and uses for the treatment of airway diseases and for the delivery of airway drugs | The University of North Carolina at Chapel Hill (US) | 2010-12-08 | — | — | EP | claimed |
| CN-118344348-A | Heterocyclic substituted quinazoline and preparation method and application thereof | 苏州泽璟生物制药股份有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118344386-A | Substituted bridged ring inhibitors and preparation method and application thereof | 苏州泽璟生物制药股份有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118324867-A | Novel cyclosporin derivatives and uses thereof | 美国科技环球有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-115605477-B | Pyrazolo [1,5-a ] pyridine derivative, preparation method, composition and application thereof | 深圳众格生物科技有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-118221660-A | Compound for treating cardiovascular and cerebrovascular diseases and preparation method and application thereof | 台州永健医药科技有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-118201642-A | Linker for antibody drug conjugates | 奥隆制药 | 2024-06-14 | — | — | CN | disclosed |
| CN-118201641-A | Novel degradant-anti-CD 33 antibody conjugates | 奥隆制药 | 2024-06-14 | — | — | CN | disclosed |
| CN-118126035-A | Cycloalkyl or heterocycle substituted benzo or pyridopyridazine, and preparation method and application thereof | 苏州泽璟生物制药股份有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-116870016-B | Heteroaromatic compound and medical application thereof | 希格生科（深圳）有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-101668751-A | aspartyl protease inhibitors | SCHERING CORP | 2010-03-10 | — | — | CN | disclosed |
| CN-101631779-A | Aspartyl protease inhibitors containing a tricyclic ring system | SCHERING CORP | 2010-01-20 | — | — | CN | disclosed |
| EP-1948159-A2 | PHARMACEUTICAL GALLIUM COMPOSITIONS AND METHODS | GENTA INCORPORATED (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007055885-A2 | PHARMACEUTICAL GALLIUM COMPOSITIONS AND METHODS | GENTA INCORPORATED (US) | 2007-05-18 | — | — | WO | disclosed |
| CN-1308536-A | Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists | BRISTOL MYERS SQUIBB CO (US) | 2001-08-15 | — | — | CN | disclosed |
| EP-0068680-B1 | ANTIBIOTICS | BEECHAM GROUP PLC (GB) | 1986-09-17 | — | — | EP | disclosed |
| EP-0013617-B1 | PENICILLIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING CERTAIN OF THESE COMPOUNDS | BEECHAM GROUP PLC (GB) | 1984-07-04 | — | — | EP | disclosed |
| EP-0006688-B1 | DIMETHYL SULFOXIDE ADDUCTS OF SODIUM 6-(D(-)-ALPHA-(4-HYDROXY-1,5-NAPHTHYRIDINE-3-CARBOXAMIDO)PHENYLACETAMIDO)PENICILLANATE OR THE DERIVATIVE THEREOF BEARING A HYDROXYL GROUP AT THE P-POSITION OF THE PHENYL GROUP, METHODS FOR THEIR PREPARATION AND DECOMPOSITION, AND THEIR USE AS INTERMEDIATES FOR PURIFYING THE CRUDE PENICILLINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-05-19 | — | — | EP | disclosed |
| EP-0005006-B1 | ANTIBACTERIAL MONIC ACID C DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1981-09-02 | — | — | EP | disclosed |
| EP-0013617-A1 | Penicillin derivatives, process for their preparation and pharmaceutical compositions containing certain of these compounds | BEECHAM GROUP PLC (GB) | 1980-07-23 | — | — | EP | disclosed |