Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28182671 | 0.83 | LMNA (0.61) | LMNAF2TDP1TSHRKMT2A | |
| SCHEMBL10500491 | 0.83 | LMNA (0.47) | LMNAF2TDP1TSHRKMT2A | |
| SCHEMBL17459732 | 0.83 | LMNA (0.47) | LMNAF2TDP1TSHRKMT2A | |
| SCHEMBL2434555 | 0.83 | LMNA (0.50) | LMNAF2TDP1TSHRKMT2A | |
| SCHEMBL17459734 | 0.83 | LMNA (0.47) | LMNAF2TDP1TSHRKMT2A | |
| SCHEMBL2434553 | 0.83 | LMNA (0.50) | LMNAF2TDP1TSHRKMT2A | |
| SCHEMBL5351140 | 0.83 | LMNA (0.47) | LMNAF2TDP1TSHRKMT2A | |
| SCHEMBL27817568 | 0.83 | LMNA (0.47) | LMNAF2TDP1TSHRKMT2A | |
| SCHEMBL10540709 | 0.81 | LMNA (0.45) | LMNAF2TDP1TSHRKMT2A | |
| SCHEMBL6673178 | 0.81 | LMNA (0.45) | LMNAF2TDP1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016013033-A1 | VINYLIC 3-AMINO-1,2 DIOLS COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-01-28 | — | — | WO | disclosed |