⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20519604 | 0.89 | — | — | |
| SCHEMBL28922641 | 0.77 | — | — | |
| SCHEMBL9191025 | 0.77 | — | — | |
| SCHEMBL28595454 | 0.76 | — | — | |
| SCHEMBL11815530 | 0.76 | CHRNB2 (0.30) | — | |
| SCHEMBL16635832 | 0.74 | GABRR1 (0.37) | — | |
| SCHEMBL23706944 | 0.74 | — | — | |
| SCHEMBL20625284 | 0.74 | — | — | |
| SCHEMBL17014388 | 0.74 | — | — | |
| SCHEMBL20625136 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385945-B1 | TRIAZOLO AND TETRAZOLO PYRIMIDINE DERIVATIVES AS HNE INHIBITORS FOR TREATING COPD | BAYER IP GMBH (DE) | 2013-01-23 | — | — | EP | disclosed |
| EP-2385945-A1 | TRIAZOLO AND TETRAZOLO PYRIMIDINE DERIVATIVES AS HNE INHIBITORS FOR TREATING COPD | Bayer Pharma Aktiengesellschaft (DE) | 2011-11-16 | — | — | EP | disclosed |
| US-8041896-B2 | Virtualization platform with dedicated cache access | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2011-10-18 | — | — | US | disclosed |
| WO-2010078953-A1 | TRIAZOLO AND TETRAZOLO PYRIMIDINE DERIVATIVES AS HNE INHIBITORS FOR TREATING COPD | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-07-15 | — | — | WO | disclosed |
| EP-1504005-A2 | SUBSTITUTED PYRAZOLO-PYRIMIDINE-4-ONES | Bayer CropScience AG (DE) | 2005-02-09 | — | — | EP | disclosed |
| WO-2003093269-A2 | SUBSTITUTED PYRAZOLO-PYRIMIDINE-4-ONES | BAYER CROPSCIENCE AG (DE) | 2003-11-13 | — | — | WO | disclosed |
| EP-0743299-B1 | Process for the preparation of 2-fluorocyclopropylamine sulfonic acid salts | BAYER AG (DE) | 1999-09-15 | — | — | EP | disclosed |
| EP-0743299-A1 | Process for the preparation of 2-fluorocyclopropylamine sulfonic acid salts and the chemical compound 2-fluorocyclopropylisocyanate | BAYER AG (DE) | 1996-11-20 | — | — | EP | disclosed |
| EP-0533013-B1 | Process for the production of 1-fluor-cyclopropane-1-carboxylic acid | BAYER AG (DE) | 1995-10-18 | — | — | EP | disclosed |
| EP-0564810-B1 | Fungicidal azolylmethyl-fluorocyclopropyl derivatives | BAYER AG (DE) | 1994-11-02 | — | — | EP | disclosed |
| EP-0564810-A1 | Fungicidal azolylmethyl-fluorocyclopropyl derivatives | BAYER AG (DE) | 1993-10-13 | — | — | EP | disclosed |
| EP-0533013-A2 | Process for the production of 1-fluor-cyclopropane-1-carboxylic acid | BAYER AG (DE) | 1993-03-24 | — | — | EP | disclosed |