SCHEMBL17460100

SCHEMBL17460100

N[C@@H](Cc1ccccc1)C(=O)OCCCCCCCCO

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.53
ALPI P09923 1/20 0.53
PKM P14618 1/20 0.53
PTGS1 P23219 1/20 0.53
XIAP P98170 1/20 0.53
LTA4H P09960 1/20 0.48
SLC15A1 P46059 2/20 0.46
ITGB3 P05106 1/20 0.46
ITGA2B P08514 1/20 0.46
LMNA P02545 1/20 0.44
SLC1A3 P43003 2/20 0.43
SLC1A2 P43004 2/20 0.43
SLC1A1 P43005 2/20 0.43
TYR P14679 2/20 0.42
HDAC8 Q9BY41 2/20 0.42
SRR Q9GZT4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15271156 0.94 SLC7A5 (0.56) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL26231121 0.94 ALPI (0.59) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL15590174 0.94 ALPI (0.59) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL19167232 0.94 ALPI (0.59) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL14095415 0.94 ALPI (0.59) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL6368998 0.92 ALPI (0.61) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL14095409 0.89 ALPI (0.61) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL7019120 0.87 SLC7A5 (0.59) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL1147651 0.87 SLC7A5 (0.59) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL25180576 0.87 TYR (0.55) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10414864-B2 Degradable amino acid-based poly (ester urea) copolymer adhesives THE UNIVERSITY OF AKRON (US) 2019-09-17 US disclosed
US-20170210852-A1 DEGRADABLE AMINO ACID-BASED POLY (ESTER UREA) COPOLYMER ADHESIVES THE UNIVERSITY OF AKRON (US) 2017-07-27 US disclosed
EP-3171880-A1 DEGRADABLE AMINO ACID-BASED POLY(ESTER UREA) COPOLYMER ADHESIVES The University of Akron (US) 2017-05-31 EP disclosed
WO-2016014471-A1 DEGRADABLE AMINO ACID-BASED POLY(ESTER UREA) COPOLYMER ADHESIVES THE UNIVERSITY OF AKRON (US) 2016-01-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170210852-A1 DEGRADABLE AMINO ACID-BASED POLY (ESTER UREA) COPOLYMER ADHESIVES PNMT, UBE3A, PCNA SLC7A5 223/4885ALPI 3036/4885PKM 858/4885
US-10414864-B2 Degradable amino acid-based poly (ester urea) copolymer adhesives PNMT, UBE3A, PCNA SLC7A5 223/4885ALPI 3036/4885PKM 858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.