Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17460337 | 1.00 | PLA2G7 (0.41) | PLA2G7GRM2 | |
| SCHEMBL17467732 | 1.00 | PLA2G7 (0.41) | PLA2G7GRM2 | |
| SCHEMBL17460335 | 0.92 | PLA2G7 (0.46) | PLA2G7GRM2 | |
| SCHEMBL17467730 | 0.92 | PLA2G7 (0.46) | PLA2G7GRM2 | |
| SCHEMBL16775594 | 0.92 | PLA2G7 (0.46) | PLA2G7GRM2 | |
| SCHEMBL17467753 | 0.90 | PLA2G7 (0.43) | PLA2G7 | |
| SCHEMBL17467718 | 0.90 | PLA2G7 (0.43) | PLA2G7 | |
| SCHEMBL17460295 | 0.90 | PLA2G7 (0.39) | PLA2G7GRM2 | |
| SCHEMBL17467735 | 0.87 | PLA2G7 (0.47) | PLA2G7GRM2 | |
| SCHEMBL17467723 | 0.87 | PLA2G7 (0.47) | PLA2G7GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016012916-A1 | 1,2,3,5-TETRAHYDROIMIDAZO[1,2-C]PYRIMIDINE DERIVATIVES USEFUL IN THE TREATMENT OF DISEASES AND DISORDERS MEDIATED BY LP-PLA2 | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2016-01-28 | — | — | WO | disclosed |