Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17200539 | 0.94 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL14137081 | 0.94 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL14062371 | 0.94 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL14137095 | 0.92 | DGAT1 (0.85) | DGAT1 | |
| SCHEMBL14137314 | 0.92 | DGAT1 (0.83) | DGAT1 | |
| SCHEMBL14062379 | 0.92 | DGAT1 (0.83) | DGAT1 | |
| SCHEMBL14137316 | 0.89 | DGAT1 (0.88) | DGAT1 | |
| SCHEMBL14137328 | 0.88 | DGAT1 (0.86) | DGAT1 | |
| SCHEMBL14061801 | 0.87 | DGAT1 (0.85) | DGAT1 | |
| SCHEMBL17200611 | 0.87 | DGAT1 (0.85) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9242929-B2 | Compounds as diacylglycerol acyltransferase inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2016-01-26 | — | — | US | disclosed |