Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14060257 | 0.89 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL17530454 | 0.89 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL14137197 | 0.89 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL14059682 | 0.85 | DGAT1 (0.81) | DGAT1 | |
| SCHEMBL14137090 | 0.85 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL14060208 | 0.84 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL17200562 | 0.84 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL14060253 | 0.83 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL14137088 | 0.83 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL14060397 | 0.83 | DGAT1 (0.84) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9242929-B2 | Compounds as diacylglycerol acyltransferase inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2016-01-26 | — | — | US | disclosed |