SCHEMBL17461517

SCHEMBL17461517

C=CC(=O)Oc1ccc(-c2ccc(-c3ccc(OC(=O)C(=C)C)cc3)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.53
THRB P10828 3/20 0.50
KMT2A Q03164 2/20 0.49
ATM Q13315 1/20 0.49
HSD17B10 Q99714 1/20 0.42
PDE6D O43924 1/20 0.38
LMNA P02545 3/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 3/20 0.36
TDP1 Q9NUW8 2/20 0.34
POLB P06746 2/20 0.34
APEX1 P27695 1/20 0.34
HTT P42858 1/20 0.34
ALDH1A1 P00352 1/20 0.33
THRA P10827 1/20 0.33
PKM P14618 1/20 0.33
TGM2 P21980 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13967523 1.00 ELANE (0.53) ELANETHRBKMT2AATMHSD17B10
SCHEMBL15630690 0.95 ELANE (0.57) ELANETHRBKMT2AATMLMNA
SCHEMBL29266521 0.94 ELANE (0.59) ELANETHRBKMT2AATMHSD17B10
SCHEMBL15626982 0.92 ELANE (0.47) ELANETHRBKMT2AATMHSD17B10
SCHEMBL15624648 0.92 ELANE (0.47) ELANETHRBKMT2AATMHSD17B10
SCHEMBL22566554 0.91 ELANE (0.52) ELANETHRBKMT2AATMHSD17B10
SCHEMBL22566605 0.91 THRB (0.61) ELANETHRBKMT2AATMHSD17B10
SCHEMBL22566612 0.91 THRB (0.61) ELANETHRBKMT2AATMHSD17B10
SCHEMBL22566607 0.91 ELANE (0.52) ELANETHRBKMT2AATMHSD17B10
SCHEMBL20312079 0.91 ELANE (0.52) ELANETHRBKMT2AATMHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2977428-B1 POLYMERIZABLE COMPOUND-CONTAINING LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DAINIPPON INK & CHEMICALS (JP) 2018-05-02 EP disclosed
US-9725651-B2 Polymerizable compound-containing liquid crystal composition and liquid crystal display element using same DIC CORPORATION (JP) 2017-08-08 US disclosed
US-9725651-B2 Polymerizable compound-containing liquid crystal composition and liquid crystal display element using same DIC CORPORATION (JP) 2017-08-08 US disclosed
US-20160122650-A1 POLYMERIZABLE COMPOUND-CONTAINING LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2016-05-05 US disclosed
US-20160122650-A1 POLYMERIZABLE COMPOUND-CONTAINING LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2016-05-05 US disclosed
EP-2977428-A1 POLYMERIZABLE COMPOUND-CONTAINING LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC Corporation (JP) 2016-01-27 EP disclosed