Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.54 |
| ▸ | HINT1 | P49773 | 4/20 | 0.52 |
| ▸ | TGM2 | P21980 | 1/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.49 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.47 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.47 |
| ▸ | KRAS | P01116 | 5/20 | 0.47 |
| ▸ | GSK3A | P49840 | 2/20 | 0.46 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21344309 | 0.94 | NT5E (0.55) | NT5EHINT1TGM2TAS1R3TAS1R1 | |
| SCHEMBL15832464 | 0.93 | HPGD (0.56) | NT5EHINT1TGM2TAS1R3TAS1R1 | |
| SCHEMBL33190 | 0.92 | NT5E (0.53) | NT5EHINT1TGM2TAS1R3TAS1R1 | |
| SCHEMBL12015141 | 0.92 | NT5E (0.53) | NT5EHINT1TGM2TAS1R3TAS1R1 | |
| SCHEMBL12590073 | 0.92 | NT5E (0.53) | NT5EHINT1TGM2TAS1R3TAS1R1 | |
| SCHEMBL16587690 | 0.90 | HINT1 (0.57) | NT5EHINT1TGM2TAS1R3TAS1R1 | |
| SCHEMBL12015139 | 0.90 | HINT1 (0.57) | NT5EHINT1TGM2TAS1R3TAS1R1 | |
| SCHEMBL12015142 | 0.90 | HINT1 (0.51) | NT5EHINT1TGM2TAS1R3TAS1R1 | |
| SCHEMBL12590077 | 0.90 | HINT1 (0.51) | NT5EHINT1TGM2TAS1R3TAS1R1 | |
| SCHEMBL33175 | 0.90 | HINT1 (0.51) | NT5EHINT1TGM2TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2386636-B1 | ENA NUCLEIC ACID DRUGS MODIFYING SPLICING IN MRNA PRECURSOR | MATSUO MASAFUMI (JP) | 2016-01-27 | — | — | EP | disclosed |