Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.35 |
| ▸ | CA1 | P00915 | 5/20 | 0.35 |
| ▸ | CA2 | P00918 | 5/20 | 0.35 |
| ▸ | CA9 | Q16790 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CTH | P32929 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17662502 | 0.85 | FAAH (0.45) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL13449666 | 0.76 | TDP1 (0.40) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL14547041 | 0.76 | PAOX (0.38) | TDP1USP2ALDH1A1 | |
| SCHEMBL12185697 | 0.76 | KMT2A (0.42) | TDP1USP2ALDH1A1 | |
| SCHEMBL23223992 | 0.76 | TDP1 (0.52) | TDP1USP2ALDH1A1 | |
| SCHEMBL17883988 | 0.75 | USP2 (0.35) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL9432728 | 0.75 | TDP1 (0.48) | TDP1ALDH1A1 | |
| SCHEMBL12841281 | 0.75 | TDP1 (0.48) | TDP1ALDH1A1 | |
| SCHEMBL9432732 | 0.75 | TDP1 (0.48) | TDP1ALDH1A1 | |
| SCHEMBL336514 | 0.75 | TDP1 (0.48) | TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9242010-B2 | Living copolymer-protein/peptide hybrids for biomedical applications | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2016-01-26 | — | — | US | disclosed |