Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 14/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL255110 | 0.86 | HSD17B10 (0.43) | HSD17B10TSHRKDM4ERAB9AALDH1A1 | |
| SCHEMBL255976 | 0.86 | HSD17B10 (0.34) | HSD17B10TSHRKDM4ERAB9AALDH1A1 | |
| SCHEMBL174618 | 0.77 | HSD17B10 (0.41) | HSD17B10TSHRKDM4ERAB9AALDH1A1 | |
| SCHEMBL255154 | 0.75 | KDM4E (0.46) | HSD17B10TSHRKDM4ERAB9AALDH1A1 | |
| SCHEMBL174272 | 0.75 | HSD17B10 (0.38) | HSD17B10TSHRKDM4ERAB9AALDH1A1 | |
| SCHEMBL255975 | 0.75 | HSD17B10 (0.34) | HSD17B10TSHRKDM4ERAB9AALDH1A1 | |
| SCHEMBL22617515 | 0.73 | TRPM8 (0.43) | HSD17B10KDM4ERAB9AALDH1A1NPC1 | |
| SCHEMBL10246954 | 0.72 | HSD17B10 (0.39) | HSD17B10TSHRKDM4ERAB9AALDH1A1 | |
| SCHEMBL254828 | 0.71 | HSD17B10 (0.39) | HSD17B10TSHRKDM4ERAB9AALDH1A1 | |
| SCHEMBL255641 | 0.71 | HSD17B10 (0.39) | HSD17B10TSHRKDM4ERAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611299-A1 | PESTICIDAL COMPOSITIONS | Dow AgroSciences LLC (US) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012030681-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-03-08 | — | — | WO | disclosed |