Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 known ✓ | P32745 | 1/20 | 0.31 |
| ▸ | PRCP | P42785 | 7/20 | 0.35 |
| ▸ | HPGDS | O60760 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1745776 | 0.96 | PRCP (0.34) | PRCPHPGDS | |
| SCHEMBL1745558 | 0.90 | PRCP (0.37) | PRCPHPGDSSSTR3CYP1A2CYP3A4 | |
| SCHEMBL15673755 | 0.90 | PRCP (0.37) | PRCPHPGDSSSTR3CYP1A2CYP3A4 | |
| Acetic Acid SCHEMBL1746999 | 0.84 | PRCP (0.41) | PRCPSSTR3CYP3A4CYP2C9 | |
| Acetic Acid SCHEMBL4980229 | 0.80 | PRCP (0.51) | PRCPCYP1A2CYP3A4CYP2D6CYP2C9 | |
| Acetic Acid SCHEMBL3344304 | 0.78 | PRCP (0.38) | PRCPSSTR3CYP3A4CYP2C9 | |
| SCHEMBL12175283 | 0.78 | MAPK13 (0.40) | PRCPHPGDSSSTR3 | |
| SCHEMBL13635780 | 0.78 | MAPK13 (0.40) | PRCPHPGDSSSTR3 | |
| SCHEMBL18171455 | 0.77 | CYP3A4 (0.63) | PRCPCYP1A2CYP3A4CYP2D6CYP2C9 | |
| Acetic Acid SCHEMBL1746326 | 0.77 | PRCP (0.47) | PRCPHPGDSCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385048-A1 | Hepatitis C virus inhibitors | Bristol-Myers Squibb Company (US) | 2011-11-09 | — | — | EP | disclosed |
| US-20110268697-A1 | Hepatitis C Virus Inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2011-11-03 | — | — | US | disclosed |
| US-20110252687-A1 | Canting Vertical Fore Grip with Bipod | GRIP POD SYSTEMS, LLC | 2011-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110268697-A1 | Hepatitis C Virus Inhibitors | HAVCR2, PYGL, HCCS | SSTR3 4672/4885PRCP 190/4885HPGDS 582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.