Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17463933 | 0.95 | MAPT (0.47) | SIRT2SIRT1TDP1CYP3A4TAAR1 | |
| SCHEMBL17454796 | 0.92 | SIRT2 (0.54) | SIRT2SIRT1TDP1CYP3A4HSD17B10 | |
| SCHEMBL18731241 | 0.91 | SIRT2 (0.55) | SIRT2SIRT1TDP1CYP3A4HSD17B10 | |
| SCHEMBL24911411 | 0.87 | SIRT2 (0.55) | SIRT2SIRT1TDP1CYP3A4HSD17B10 | |
| SCHEMBL20317131 | 0.87 | SIRT2 (0.55) | SIRT2SIRT1TDP1CYP3A4HSD17B10 | |
| SCHEMBL17661463 | 0.86 | SIRT2 (0.49) | SIRT2SIRT1TDP1SYKAKR1C3 | |
| SCHEMBL17463908 | 0.86 | ALDH1A1 (0.50) | SIRT2SIRT1TDP1CYP3A4TAAR1 | |
| SCHEMBL31734559 | 0.85 | SIRT2 (0.54) | SIRT2SIRT1TDP1CYP3A4HSD17B10 | |
| SCHEMBL2790237 | 0.85 | SIRT2 (0.57) | SIRT2SIRT1TDP1CYP3A4HSD17B10 | |
| SCHEMBL31029800 | 0.85 | SIRT2 (0.57) | SIRT2SIRT1TDP1CYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016013875-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2016-01-28 | — | — | WO | disclosed |