Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737634 | 0.82 | ALDH1A1 (0.38) | KDM4EHSD17B10PTPN1ESR1SCN5A | |
| SCHEMBL7538049 | 0.80 | PIM1 (0.53) | PIM1HTTKDM4EGAAHSD17B10 | |
| SCHEMBL10738010 | 0.76 | PTPN1 (0.44) | HTTKDM4EGAAHSD17B10PTPN1 | |
| Acetic Acid SCHEMBL5042428 | 0.74 | HTT (0.47) | HTTKDM4EGAAMAPTESR1 | |
| SCHEMBL8818060 | 0.74 | KDM4E (0.36) | KDM4ERAB9ALMNAALDH1A1TSHR | |
| SCHEMBL8949861 | 0.73 | PIM1 (0.50) | PIM1HTTKDM4EGAAHSD17B10 | |
| SCHEMBL11139550 | 0.73 | POLB (0.46) | KDM4EHSD17B10MAPTPTPN1ACHE | |
| SCHEMBL31268722 | 0.73 | PIM1 (0.50) | PIM1HTTKDM4EGAAHSD17B10 | |
| SCHEMBL27642137 | 0.73 | ERN1 (0.37) | MAPTALDH1A1 | |
| SCHEMBL27623412 | 0.72 | TSHR (0.50) | KDM4EGAAHSD17B10MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2386540-A1 | Novel compounds, their preparation and use | High Point Pharmaceuticals, LLC (US) | 2011-11-16 | — | — | EP | disclosed |