Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM5C | P41229 | 2/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 2/20 | 0.43 |
| ▸ | USP7 | Q93009 | 4/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17464472 | 0.91 | NAMPT (0.51) | GRIN2BNAMPTF2ALDH1A1POLB | |
| SCHEMBL17464476 | 0.86 | F2 (0.49) | GRIN2BNAMPTF2POLBKDM5C | |
| SCHEMBL17069490 | 0.86 | GRIN2B (0.51) | GRIN2BF2ALDH1A1POLBKDM5C | |
| SCHEMBL17464477 | 0.85 | KDM5C (0.45) | GRIN2BNAMPTF2POLBKDM5C | |
| SCHEMBL17453702 | 0.85 | GRK2 (0.47) | GRIN2BNAMPTF2POLBKDM5C | |
| SCHEMBL17464474 | 0.83 | F2 (0.46) | GRIN2BNAMPTF2ALDH1A1POLB | |
| SCHEMBL19362127 | 0.82 | GRK2 (0.45) | GRIN2BNAMPTF2ALDH1A1POLB | |
| SCHEMBL17453716 | 0.82 | GRK2 (0.45) | GRIN2BNAMPTF2ALDH1A1POLB | |
| SCHEMBL17464486 | 0.81 | F2 (0.44) | GRIN2BNAMPTF2POLBFAAH | |
| SCHEMBL17463703 | 0.81 | GRIN2B (0.50) | GRIN2BF2ALDH1A1POLBKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9771374-B2 | Benzimidazole retinoic acid receptor-related orphan receptor modulators and uses thereof | INNOV17 LLC (US) | 2017-09-26 | — | — | US | disclosed |
| US-9771374-B2 | Benzimidazole retinoic acid receptor-related orphan receptor modulators and uses thereof | INNOV17 LLC (US) | 2017-09-26 | — | — | US | disclosed |
| US-9771374-B2 | Benzimidazole retinoic acid receptor-related orphan receptor modulators and uses thereof | INNOV17 LLC (US) | 2017-09-26 | — | — | US | disclosed |
| US-20170190712-A1 | BENZIMIDAZOLE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF | INNOV17 LLC | 2017-07-06 | — | — | US | disclosed |
| US-20170190712-A1 | BENZIMIDAZOLE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF | INNOV17 LLC | 2017-07-06 | — | — | US | disclosed |
| US-20160024052-A1 | BENZIMIDAZOLE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF | INNOV17 LLC (US) | 2016-01-28 | — | — | US | disclosed |
| US-20160024052-A1 | BENZIMIDAZOLE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF | INNOV17 LLC (US) | 2016-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190712-A1 | BENZIMIDAZOLE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF | RARB, RARA, RARG | GRIN2B 1369/4885NAMPT 1609/4885F2 4880/4885 |
| US-20160024052-A1 | BENZIMIDAZOLE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF | RARB, RARA, RARG | GRIN2B 1369/4885NAMPT 1609/4885F2 4880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.