Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.57 |
| ▸ | PPARG | P37231 | 8/20 | 0.57 |
| ▸ | PPARD | Q03181 | 5/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1745593 | 0.80 | FFAR1 (0.67) | FFAR1FFAR4 | |
| SCHEMBL1745591 | 0.80 | FFAR1 (0.51) | PPARAPPARGFFAR1FFAR4 | |
| SCHEMBL1746694 | 0.79 | FFAR1 (0.56) | PPARAPPARGFFAR1FFAR4CETP | |
| SCHEMBL12571107 | 0.78 | FFAR1 (0.52) | FFAR1FFAR4 | |
| SCHEMBL28087440 | 0.78 | MME (0.60) | PPARAPPARGPPARDFFAR1MME | |
| SCHEMBL1746690 | 0.75 | FFAR1 (0.48) | PPARGFFAR1FFAR4CETP | |
| SCHEMBL10795614 | 0.74 | MMP1 (0.54) | PPARAPPARGFFAR1FFAR4MME | |
| SCHEMBL28893490 | 0.73 | CYP1A2 (0.65) | PPARAPPARGFFAR1FFAR4MME | |
| SCHEMBL1746794 | 0.73 | TDP1 (0.50) | PPARAPPARGPPARD | |
| SCHEMBL1745480 | 0.72 | FFAR1 (0.69) | FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385032-A1 | GPR40 Receptor function regulator | Takeda Pharmaceutical Company Limited (JP) | 2011-11-09 | — | — | EP | disclosed |
| US-7960369-B2 | Receptor function regulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-06-14 | — | — | US | disclosed |