Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.44 |
| ▸ | GRM5 | P41594 | 3/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17156967 | 0.79 | HRH3 (0.42) | HRH3GRM5 | |
| SCHEMBL176096 | 0.78 | HRH3 (0.37) | HRH3 | |
| SCHEMBL17156961 | 0.74 | GRM5 (0.40) | GRM5 | |
| SCHEMBL15738751 | 0.74 | NPC1 (0.46) | HRH3GRM5CYP2D6 | |
| Cadaverine Tartrate SCHEMBL15737781 | 0.74 | GRM5 (0.39) | HRH3GRM5 | |
| SCHEMBL165592 | 0.73 | HRH3 (0.45) | HRH3GRM5 | |
| SCHEMBL17156958 | 0.72 | GRM5 (0.51) | HRH3GRM5 | |
| SCHEMBL17156963 | 0.72 | GRM5 (0.48) | HRH3GRM5 | |
| SCHEMBL17156955 | 0.71 | GRM5 (0.50) | HRH3GRM5 | |
| SCHEMBL17156954 | 0.71 | GRM5 (0.47) | HRH3GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611444-A1 | HETEROCYCLYL COMPOUNDS AS HISTAMINE H3 RECEPTOR LIGANDS | Suven Life Sciences Limited (IN) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012029070-A1 | HETEROCYCLYL COMPOUNDS AS HISTAMINE H3 RECEPTOR LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2012-03-08 | — | — | WO | disclosed |