SCHEMBL17468362

SCHEMBL17468362

Cc1ccccc1N(C1=CC=CC(C)C1)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.31
GAA P10253 2/20 0.31
TP53 P04637 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
APP P05067 1/20 0.31
CRHBP P24387 1/20 0.31
CRHR2 Q13324 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19289314 0.84
SCHEMBL17993815 0.82 APP (0.35) ALDH1A1GAAAPP
SCHEMBL23193275 0.79 ALDH1A1 (0.34) ALDH1A1APPCRHBPCRHR2LMNA
SCHEMBL21616026 0.79 ALDH1A1 (0.34) ALDH1A1APPCRHBPCRHR2LMNA
SCHEMBL13780636 0.79 ALDH1A1 (0.34) ALDH1A1APPCRHBPCRHR2LMNA
SCHEMBL18323805 0.79 ALDH1A1 (0.34) ALDH1A1APPCRHBPCRHR2LMNA
SCHEMBL22294817 0.78 ALDH1A1 (0.33) ALDH1A1APPLMNA
SCHEMBL25757301 0.78
SCHEMBL20749579 0.78
SCHEMBL25111267 0.77 APP (0.31) APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3053910-A1 ANILINE DERIVATIVES AND USES THEREOF Nissan Chemical Industries, Ltd. (JP) 2016-08-10 EP disclosed
WO-2016013533-A1 CHARGE TRANSPORT MATERIAL 日産化学工業株式会社 2016-01-28 WO disclosed