SCHEMBL17468844

SCHEMBL17468844

N#Cc1cccc(Nc2ccc(-c3cccc(-c4ccccc4)c3)cc2-c2ccccc2)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLK Q9H2G2 3/20 0.51
STK10 O94804 2/20 0.51
ALDH1A1 P00352 3/20 0.48
KDM4E B2RXH2 2/20 0.48
GAA P10253 1/20 0.48
ABCG2 Q9UNQ0 6/20 0.47
FLT1 P17948 1/20 0.47
FLT4 P35916 1/20 0.47
KDR P35968 1/20 0.47
ACP1 P24666 2/20 0.46
PDE4B Q07343 1/20 0.45
MAPT P10636 2/20 0.44
ADORA2B P29275 1/20 0.43
ADORA1 P30542 1/20 0.43
ACLY P53396 2/20 0.43
KCNA5 P22460 1/20 0.43
MEN1 O00255 1/20 0.41
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41
CYP1A2 P05177 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17468838 0.96 STK10 (0.47) SLKSTK10ALDH1A1KDM4EGAA
SCHEMBL17468668 0.94 ALDH1A1 (0.51) SLKSTK10ALDH1A1KDM4EGAA
SCHEMBL17573763 0.93 SLK (0.46) SLKSTK10ALDH1A1KDM4EGAA
SCHEMBL17464111 0.92 KDM4E (0.48) SLKSTK10ALDH1A1KDM4EGAA
SCHEMBL17463471 0.90 KDM4E (0.52) SLKSTK10ALDH1A1KDM4EGAA
SCHEMBL17573769 0.90 KDM4E (0.52) SLKSTK10ALDH1A1KDM4EGAA
SCHEMBL18767416 0.89 KDM4E (0.50) SLKSTK10ALDH1A1KDM4EGAA
SCHEMBL17454741 0.87 ABCG2 (0.50) ALDH1A1KDM4EGAAABCG2ACP1
SCHEMBL17468982 0.87 ABCG2 (0.48) SLKSTK10ALDH1A1KDM4EGAA
SCHEMBL17454751 0.86 SLK (0.47) SLKSTK10ALDH1A1KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017065419-A1 ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2017-04-20 WO disclosed
WO-2016013867-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2016-01-28 WO disclosed