Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15482694 | 0.84 | HCAR2 (0.47) | TSHRALOX15ATMNPSR1HPGD | |
| SCHEMBL15482543 | 0.82 | SMN1; SMN2 (0.36) | TSHRALOX15ATMNPSR1 | |
| SCHEMBL15482737 | 0.81 | ATM (0.57) | TSHRATMNPSR1HPGDHCAR2 | |
| SCHEMBL15482698 | 0.79 | TDP1 (0.40) | TSHRALOX15 | |
| SCHEMBL15482535 | 0.79 | NPSR1 (0.52) | TSHRALOX15ATMNPSR1HCAR2 | |
| SCHEMBL10073610 | 0.79 | NPSR1 (0.52) | TSHRALOX15ATMNPSR1HCAR2 | |
| SCHEMBL19847299 | 0.79 | TSHR (0.54) | TSHRALOX15ATMACHENPSR1 | |
| SCHEMBL28541277 | 0.77 | TSHR (0.44) | TSHRATMACHEHCAR2 | |
| SCHEMBL7265941 | 0.75 | TSHR (0.50) | TSHRALOX15ATMACHENPSR1 | |
| SCHEMBL7265950 | 0.75 | TSHR (0.50) | TSHRALOX15ATMACHENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016012362-A1 | SUBSTITUTED CYANO CYCLOALKYL PENTA-2,4-DIENES, CYANO CYCLOALKYL PENT-2-EN-4-YNES, CYANO HETEROCYCLYL PENTA-2,4-DIENES AND CYANO HETEROCYCLYL PENT-2-EN-4-YNES AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-01-28 | — | — | WO | disclosed |