Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
| ▸ | CBLB | Q13191 | 1/20 | 0.31 |
| ▸ | F13A1 | P00488 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17469080 | 0.78 | KDM4E (0.43) | KDM4EMAPK1HIF1ATSHRPAOX | |
| SCHEMBL12310434 | 0.71 | — | — | |
| SCHEMBL21845015 | 0.67 | KDM4E (0.48) | KDM4EMAPK1HIF1ATSHRPAOX | |
| SCHEMBL17469079 | 0.67 | MAPK1 (0.39) | KDM4EMAPK1HIF1ATSHRPAOX | |
| SCHEMBL887478 | 0.66 | KDM4E (0.46) | KDM4EMAPK1HIF1ATSHRPAOX | |
| SCHEMBL21064450 | 0.66 | KDM4E (0.46) | KDM4EMAPK1HIF1ATSHRPAOX | |
| SCHEMBL21419978 | 0.66 | KDM4E (0.46) | KDM4EMAPK1HIF1ATSHRPAOX | |
| SCHEMBL4939278 | 0.66 | ADRA1A (0.47) | KDM4EMAPK1HIF1ATSHRPAOX | |
| SCHEMBL10078297 | 0.66 | KDM4E (0.38) | KDM4EMAPK1HIF1ATSHRPAOX | |
| SCHEMBL20887486 | 0.65 | KDM4E (0.52) | KDM4EMAPK1HIF1ATSHRPAOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016014463-A1 | HETEROCYCLIC CARBOXYLIC ACIDS AS ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-01-28 | — | — | WO | disclosed |