Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.74 |
| ▸ | HTT | P42858 | 5/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.74 |
| ▸ | JAK2 | O60674 | 1/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.72 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11495864 | 0.87 | POLB (0.78) | POLBLMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL23451628 | 0.86 | POLB (0.75) | POLBLMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL3591952 | 0.84 | POLB (0.72) | POLBLMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL15904002 | 0.83 | POLB (0.71) | POLBLMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL19263031 | 0.82 | POLB (0.69) | POLBLMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL6404124 | 0.82 | POLB (0.69) | POLBLMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL11485906 | 0.81 | POLB (0.68) | POLBLMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL14452037 | 0.81 | POLB (0.68) | POLBLMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL19263033 | 0.81 | POLB (0.67) | POLBLMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL19263057 | 0.80 | POLB (0.66) | POLBLMNASMN1; SMN2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3280707-B1 | BICYCLIC QUINAZOLINONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2023-12-20 | — | — | EP | claimed |
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |