Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17469084 | 0.84 | POLB (1.00) | POLBSMN1; SMN2CYP1A2LMNAHTT | |
| SCHEMBL6623576 | 0.82 | POLB (0.56) | POLBSMN1; SMN2CYP1A2LMNAHTT | |
| SCHEMBL4680699 | 0.81 | POLB (0.48) | POLBSMN1; SMN2CYP1A2LMNAHTT | |
| SCHEMBL23451628 | 0.81 | POLB (0.75) | POLBSMN1; SMN2CYP1A2LMNAHTT | |
| SCHEMBL3582354 | 0.80 | POLB (0.54) | POLBSMN1; SMN2CYP1A2LMNAHTT | |
| SCHEMBL4684193 | 0.80 | POLB (0.54) | POLBSMN1; SMN2CYP1A2LMNAHTT | |
| SCHEMBL15904002 | 0.78 | POLB (0.71) | POLBSMN1; SMN2CYP1A2LMNAHTT | |
| SCHEMBL4683349 | 0.77 | NOTUM (0.66) | POLBSMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL6407414 | 0.75 | MAPT (0.47) | POLBSMN1; SMN2CYP1A2LMNAHTT | |
| SCHEMBL4684429 | 0.74 | NOTUM (0.66) | POLBSMN1; SMN2CYP1A2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100075984-A1 | DICARBONYLIC COMPOUNDS WITH ANTIBACTERIAL ACTIVITY | LABORATORIOS SALVAT, S.A. (ES) | 2010-03-25 | — | — | US | disclosed |
| EP-1437349-B9 | SUBSTITUTED ISOXAZOLES AND THE USE THEREOF AS ANTIBIOTICS | S A L V A T LAB SA (ES) | 2008-09-10 | — | — | EP | disclosed |
| EP-1437349-B1 | SUBSTITUTED ISOXAZOLES AND THE USE THEREOF AS ANTIBIOTICS | S A L V A T LAB SA (ES) | 2007-08-15 | — | — | EP | disclosed |
| US-20050014806-A1 | Substituted isoxazoles and their use as antibiotics | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2005-01-20 | — | — | US | disclosed |
| EP-1437349-A1 | SUBSTITUTED ISOXAZOLES AND THE USE THEREOF AS ANTIBIOTICS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2004-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100075984-A1 | DICARBONYLIC COMPOUNDS WITH ANTIBACTERIAL ACTIVITY | AHR, DDC, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | POLB 568/4885SMN1; SMN2 3098/4885CYP1A2 350/4885 |
| US-20050014806-A1 | Substituted isoxazoles and their use as antibiotics | XDH, SCO2, HAX1 | POLB 1162/4885SMN1; SMN2 3326/4885CYP1A2 102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.