Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM5A | P29375 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17469193 | 0.81 | MGAM (0.37) | KMT2AMEN1TSHRLMNAKDM4E | |
| SCHEMBL11685772 | 0.79 | KMT2A (0.54) | KMT2AMEN1TSHRLMNAKDM4E | |
| SCHEMBL17469188 | 0.72 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL64783 | 0.71 | KMT2A (0.65) | KMT2AMEN1TSHRLMNAKDM4E | |
| SCHEMBL2055295 | 0.69 | KMT2A (0.62) | KMT2AMEN1TSHRLMNAKDM4E | |
| SCHEMBL2055303 | 0.69 | KMT2A (0.62) | KMT2AMEN1TSHRLMNAKDM4E | |
| SCHEMBL2055299 | 0.69 | KMT2A (0.62) | KMT2AMEN1TSHRLMNAKDM4E | |
| SCHEMBL12791521 | 0.69 | KMT2A (0.62) | KMT2AMEN1TSHRLMNAKDM4E | |
| SCHEMBL17468972 | 0.69 | MGAM (0.32) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL15786184 | 0.68 | TSHR (0.54) | KMT2AMEN1TSHRLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016012362-A1 | SUBSTITUTED CYANO CYCLOALKYL PENTA-2,4-DIENES, CYANO CYCLOALKYL PENT-2-EN-4-YNES, CYANO HETEROCYCLYL PENTA-2,4-DIENES AND CYANO HETEROCYCLYL PENT-2-EN-4-YNES AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-01-28 | — | — | WO | disclosed |