SCHEMBL17469520

SCHEMBL17469520

NCC(=O)N[C@H]1C(C[C@H](O)CO)O[C@](OP(=O)(O)OC[C@H]2O[C@@H](n3ccc(N)nc3=O)[C@@H](O)C2O)(C(=O)O)C[C@H]1O

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 3/20 0.46
ST6GAL1 P15907 11/20 0.45
P2RY4 P51582 2/20 0.45
P2RY6 Q15077 2/20 0.45
TSHR P16473 1/20 0.43
GLA P06280 1/20 0.43
LMNA P02545 1/20 0.41
THRB P10828 1/20 0.41
MTOR P42345 1/20 0.41
MDM2 Q00987 1/20 0.41
NCOA1 Q15788 1/20 0.41
NCOA3 Q9Y6Q9 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18495198 1.00 P2RY2 (0.46) P2RY2ST6GAL1P2RY4P2RY6TSHR
SCHEMBL20068332 0.92 P2RY2 (0.43) P2RY2ST6GAL1P2RY4P2RY6TSHR
SCHEMBL24169755 0.90 P2RY2 (0.51) P2RY2ST6GAL1P2RY4P2RY6TSHR
SCHEMBL24170210 0.90 P2RY2 (0.51) P2RY2ST6GAL1P2RY4P2RY6TSHR
SCHEMBL20180415 0.90 ST6GAL1 (0.43) P2RY2ST6GAL1P2RY4P2RY6TSHR
SCHEMBL16093276 0.89 ST6GAL1 (0.47) P2RY2ST6GAL1P2RY4P2RY6TSHR
SCHEMBL12495844 0.89 ST6GAL1 (0.47) P2RY2ST6GAL1P2RY4P2RY6TSHR
SCHEMBL17021020 0.89 ST6GAL1 (0.47) P2RY2ST6GAL1P2RY4P2RY6TSHR
SCHEMBL18495200 0.89 ST6GAL1 (0.47) P2RY2ST6GAL1P2RY4P2RY6TSHR
SCHEMBL10044129 0.89 ST6GAL1 (0.47) P2RY2ST6GAL1P2RY4P2RY6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170096655-A1 COAGULATION FACTOR VII POLYPEPTIDES NOVO NORDISK HEALTHCARE AG (CH) 2017-04-06 US disclosed
US-20160024487-A1 THROMBIN SENSITIVE COAGULATION FACTOR X MOLECULES NOVO NORDISK A/S (DK) 2016-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170096655-A1 COAGULATION FACTOR VII POLYPEPTIDES F7, F13B, HABP2 P2RY2 4167/4885ST6GAL1 524/4885P2RY4 3943/4885
US-20160024487-A1 THROMBIN SENSITIVE COAGULATION FACTOR X MOLECULES F11, F5, F13B P2RY2 4406/4885ST6GAL1 1027/4885P2RY4 4376/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.